Publications by authors named "Bbumba Patrick"
Article Synopsis
- Recent advancements in cancer therapy emphasize reprogramming the immune tumor microenvironment instead of just targeting cancer cells directly.
- *Epidrugs, which target epigenetic regulation, are crucial for enhancing the immune response against tumors and modifying how cancer cells are recognized by the immune system.
- *Natural compounds are being highlighted as effective epigenetic modulators with potential for improving cancer treatment by harnessing their immunomodulatory effects.*
Cancer immunotherapy has made breakthrough progress in cancer treatment. However, only a subset of patients benefits from immunotherapy. Given their unique structure, composition, and interactions with the immune system, carbon nanomaterials have recently attracted tremendous interest in their roles as modulators of antitumor immunity.
View Article and Find Full Text PDFEpigenetic remodeling and metabolic reprogramming, two well-known cancer hallmarks, are highly intertwined. In addition to their abilities to confer cancer cell growth advantage, these alterations play a critical role in dynamically shaping the tumor microenvironment and antitumor immunity. Recent studies point toward the interplay between epigenetic regulation and metabolic rewiring as a potentially targetable Achilles' heel in cancer.
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