Current Guidelines on Antithrombotic Management in Patients Undergoing Gastrointestinal Endoscopy.

Endoscopic procedure is commonly used to make diagnosis or therapy. Endoscopy has risk on the procedure or after the procedure. Patient with antithrombotic therapy, both antiplatelet and/or anticoagulant, for underlying diseases has higher risk for bleeding and thromboembolic events in this procedure.

The Value of Caspase-3 after the Application of Leaf Extract in COLO-205 Colorectal Cancer Cell Line.

, commonly known as soursop, contains annonacin, acetogenin, and polyphenol which are known to have chemopreventive effects on cancer. In this study, we tend to evaluate the apoptosis-inducing effect of soursop () leaf extract on the colorectal cancer cell line COLO-205 through the activities of caspase-3 which is a marker of cell apoptosis. Cell cultures were incubated with soursop leaf with a concentration of 10 g/ml and then compared with those of the incubated positive control leucovorin 10 g/ml and placebo as a negative control.