Acceptability of the Kangaroo Mother Care at the University Hospital of Treichville in Côte d'Ivoire.

Background: Kangaroo Mother Care (KMC) is a low-tech, highimpact intervention for preterm and low-birth-weight newborns. In 2019, Côte d'Ivoire opened its first KMC unit. We wanted to determine KMC's acceptability in Côte d'Ivoire after a year.

Decrease in liver cancer incidence rates in Bamako, Mali over 28 years of population-based cancer registration (1987-2015).

Background: Primary liver cancer is common in West Africa due to endemic risk factors. However, epidemiological studies of the global burden and trends of liver cancer are limited. We report changes in trends of the incidence of liver cancer over a period of 28 years using the population-based cancer registry of Bamako, Mali.

Hypovitaminosis D in patients with type 2 diabetes: risk factors and association with glycemic control and established microvascular complications.

Introduction: Several studies reported than vitamin D deficiency increases the risk of macrovascular and microvascular disease in patients with type 2 diabetes (T2DM). We investigated the plasma levels of 25OHD in adult patients T2DM, risk factors for 25OHD deficiency and the relationship between 25OHD, glycemic control and chronic complications of T2DM.

Methods: A cross-sectional study was carried out, in which 25OHD levels were evaluated in adult patients (over 18 years) with T2DM.

Feasibility of the eight or more contacts of the WHO new antenatal care model in Cote d'Ivoire: an antenatal care providers' perspective.

This paper examines the feasibility of the eight or more ANC contacts in Cote d'Ivoire through a qualitative study among twenty antenatal care providers through individual interviews. The eight or more ANC contacts were found useful as they will allow a better follow up of the pregnancy. Main barriers were: the lack of training on the 2016 WHO ANC model, the late initiation of ANC and the fear of increased workload.

Predictors for expired CO in neonatal bag-mask ventilation at birth: observational study.

Background: Expired carbon dioxide (ECO) indicates degree of lung aeration immediately after birth. Favourable ventilation techniques may be associated with higher ECO and a faster increase. Clinical condition will however also affect measured values.

Socio-demographic and reproductive determinants of cervical neoplasia in seven sub-Sahara African countries.

Background: Since most human papilloma virus (HPV) infections regress without any intervention, HPV is a necessary but may not be a solely sufficient cause of cervical intraepithelial neoplasia (CIN) and cervical cancer. Hence, the influence of cofactors on progression from cervical HPV infection to high-grade CIN and invasive cervical cancer has been a subject of intensive research.

Objective: We assessed the effect of socio-demographic and sexual reproductive factors on the prevalence of invasive cervical cancer and CIN diagnosed in cross-sectional cervical cancer screening projects carried out in seven sites of different sub-Saharan countries.

Breast cancer in pre-menopausal women in West Africa: analysis of temporal trends and evaluation of risk factors associated with reproductive life.

Background: In West Africa, trends and risk factors for breast cancer (BC) have been rarely studied.

Methods: Here we have analyzed trends of BC over two periods in two population-based cancer registries, in Mali-Bamako (1987-1997; 1998-2009) and in The Gambia (1988-1997; 1998-2006). We have conducted a case-control study (n = 253 cases, 249 controls) on risk factors associated with reproductive life stratified by menopausal status in Bamako.

[Colon amyloidosis secondary to tuberculosis: Case report and review of the literature].

The authors report the first case of amyloidosis diagnosed by histology and documented in Mali. The patient was a young lady of 31 years old who was hospitalized in internal medicine at the University Hospital of "Point G" for edema and ascites syndrome. She had a history of diarrhea, fever, vomiting, exercise dyspnea and diffused abdominal pain.

Can visual cervical screening be sustained in routine health services? Experience from Mali, Africa.

Objective: To assess the feasibility of sustaining visual cervical screening and treatment services in Mali, and to evaluate their performance and impact in improving the provision of cervical cancer control, following an initial cross-sectional study.

Design: Descriptive study.

Setting: Bamako area, Mali.

Metallothionein expression in colorectal cancer: relevance of different isoforms for tumor progression and patient survival.

Metallothioneins are a family of small, cysteine-rich proteins with many functions. Immunohistochemical evaluation of all metallothionein 1 + 2 isoforms in colorectal tumors has demonstrated an important down-regulation compared with normal tissue, although its prognostic significance is unclear. Moreover, the contribution of individual isoforms to overall metallothionein down-regulation is not known.

Performance of colposcopy in five sub-Saharan African countries.

Objective: The performance of colposcopy provided in a screening study in five African countries was evaluated.

Design: Cross-sectional study.

Setting: Burkina Faso, Congo Brazzaville, Guinea Conakry, Mali and Niger.

[Extension of cervix cancer screening by visual methods to the community health centres in the district of Bamako].

Cervix cancer remains a public health problem in developing countries. These results are an assessment for multicentric study based on visual inspection of the cervix after application of acetiq acid (VIA) and lugol's iodine (VILI). The aim of this study is to determine the feasibility and the impact of this screening in the community health centres "CSCOM" in the district of Bamako.

[Epidemiology and morphology of breast benign tumors in Mali: about 186 cases].

Background: Mammary tumors are frequent. Benign tumors are more frequent, and are characterized by a possibility of recurrence or malignant transformation. The aim of this study was to describe the epidemiological and morphological characteristics of breast benign tumors.

[Laryngo-pharyngeal cancer at a health service of last resort in Mali: anatomo-clinical and therapeutic aspects].

The purpose of this study is to describe the clinical, anatomic and therapeutic aspects of laryngitis--pharyngeal cancers in Mali. It was a prospective, descriptive and cross sectional study which was help in the ORL and cervical facial department of the university hospital center Gabriel TOURE between April 2006 and March 2007. The study looked at 18 patients hospitalized for larynx or hypo pharynx cancer, diagnostic was confirmed histologically.

Type-specific seroprevalence of herpes simplex virus type 2 and associated risk factors in middle-aged women from 6 countries: the IARC multicentric study.

Goal: To determine type-specific seroprevalence of herpes simplex viruses (HSV-1 and HSV-2) and HSV-2 risk factors.

Study Design: Six-hundred fifty eight middle-aged control women (hospital-based in 4 of 6 countries) from a multicenter cervical cancer case-control study participated from 1985 to 1997. Type-specific serum IgG antibodies against HSV-1 and HSV-2 were detected with Western Blot.

[Anatomopathologic, clinical and radiologic aspects of benign tumors of the prostate in Mali, 759 cases].

The benign prostate tumours are dominated by prostatic adenomyoma. They are the first uro-genital pathology worldwide. The objective of this work is to describe the anatomo-pathological, clinical and radiological aspects of benign prostate tumours in Mali.

Risk factors of invasive cervical cancer in Mali.

Background: Cervical cancer is the most common cancer in women in Mali and the second commonest cause of cancer mortality.

Methods: As part of an international effort to evaluate the role of human papillomavirus (HPV) in the aetiology of cervical cancer, we conducted a hospital-based case-control study in three medical centres in Bamako during 1994-1995. A total of 82 cases (invasive cervical cancer patients) and 97 controls matched to the cases for age were included.

Distribution of composite CYP1A1 genotypes in Africans, African-Americans and Caucasians.

We present the genotype distribution of the CYP1A1 gene in a sample of over 300 subjects of various ethnic origins. Genotypes are presented as composites of eight possible alleles, taking into account the three major polymorphisms, including a recently described African-American-specific MspI RFLP. A new nomenclature system is presented for clarifying the various haplotypes.

Radical differences in CYP1A1 genotype and function.

The cytochrome P450 1A1 (CYP1A1) gene may be of critical importance in determining individual cancer susceptibility to aromatic hydrocarbons such as those in tobacco smoke. We compared the frequencies of CYP1A1 haplotypes, and complete genotypes, taking into account polymorphisms at 3 sites, including an African-specific polymorphism. No concordance was observed in Africans or African-Americans between any of the 3 polymorphisms, (Msp1 restriction fragment length polymorphism (RFLP)--'M', exon 7--'E', new RFLP--'A') in contrast to the concordance seen between the M and E polymorphisms in Caucasians and Asians.

Cancer in Mali, 1987-1988.

Results from the population cancer registry in Bamako, Mali, for the years 1987 and 1988, are presented. The age-standardized incidence for all cancers is high compared with rates reported elsewhere in West Africa (119.6 per 10(5) in males and 88.

[Ectopic spleens. About a spleen of the right iliac fossa (author's transl)].

A rare case of the presence of the spleen in the right iliac fossa is reported. The frequency and signs of ectopic and supernumerary spleens are described, the latter requiring differentiation from peritoneal splenosis. An embryological explanation for the presence of the spleen in the right iliac fossa is suggested.

Effect of active and passive immunization on the development of experimental Pseudomonas aeruginosa pyelonephritis in mice.

Experimental pyelonephritis was produced in mice by the intravenous injection of Pseudomonas aeruginosa. Immune response to infection was studied by passive hemagglutination antibody titers. Vaccination of mice with live P.

[Histopathological observations of experimental hematogenous infection with Pseudomonas aeruginosa in mice (author's transl)].

The effect of intravenous injection of Pseudomonas aeruginosa in mice was studied in various conditions : dose of bacteria injected (2.5 X 10(6) to 4.5 X 10(7)) , moment of necropsy (one hour to 4 months after infection), number of injections (one, two and eight).