Prediction and prevention of late-onset pre-eclampsia: a systematic review.

Background: Pre-eclampsia is a major cause of perinatal morbidity and mortality worldwide. Late-onset pre-eclampsia (LOP), which results in delivery ≥34 weeks gestation, is the most common type. However, there is a lack of knowledge in its prediction and prevention.

Book-Sharing for Toddlers with Clefts (BOOST): Protocol for a randomized controlled trial of a remote intervention to promote language development in children with cleft palate.

Background: Children with cleft palate, with or without cleft lip (CP±L), exhibit language delays on average compared to children without clefts. Interventions to address these disparities are scarce. In this multi-center study, Book Sharing for Toddlers with Clefts (BOOST), we will test a remote, parent-focused intervention to promote language development in children with CP±L.

Correspondence between consonant inventories obtained using modified naturalistic listening in real time (NLRT) and parent report.

Objective: The current study examined the correspondence between consonant inventories obtained using the modified NLRT approach and parent report.

Design: Prospective comparative study.

Setting: Multisite institutional.

Factors Associated with Delayed Palatoplasty Before, During, and After the COVID-19 Pandemic.

Background: Cleft palatoplasty is typically performed around 10 to 12 months of age in the US, and delays can negatively affect speech development. Early during COVID-19, elective surgeries were canceled. The aims of this study were to (1) identify overall risk factors for greater age at palatoplasty and (2) analyze delays in palatoplasty during COVID-19.

Standardization of Videorecorded Speech Samples for Children with Cleft Palate: Methods to Facilitate High-Quality Speech Outcomes Data Collection.

Background: Collection of high-quality videorecorded speech samples is essential for speech outcomes research.

Solution: Cleft palate team SLPs were trained to collect standard videorecorded speech samples in the clinic setting across 20 sites in North America. Standard training and equipment was provided.

The Falkland Islands marine ecosystem: A review of the seasonal dynamics and trophic interactions across the food web.

The Falkland Islands marine environment host a mix of temperate and subantarctic species. This review synthesizes baseline information regarding ontogenetic migration patterns and trophic interactions in relation to oceanographic dynamics of the Falkland Shelf, which is useful to inform ecosystem modelling. Many species are strongly influenced by regional oceanographic dynamics that bring together different water masses, resulting in high primary production which supports high biomass in the rest of the food web.

Genomic evidence for homoploid hybrid speciation in a marine mammal apex predator.

Hybridization is widespread and constitutes an important source of genetic variability and evolution. In animals, its role in generating novel and independent lineages (hybrid speciation) has been strongly debated, with only a few cases supported by genomic data. The South American fur seal (SAfs) is a marine apex predator of Pacific and Atlantic waters, with a disjunct set of populations in Peru and Northern Chile [Peruvian fur seal (Pfs)] with controversial taxonomic status.

Stop Consonant Production in Children with Cleft Palate After Palatoplasty.

The current study examined stop consonant production in children with cleft lip and/or palate (CP ± L) 2-6 months following palatal surgery. Prospective comparative study. Multisite institutional.

Updated clinical practice recommendations for managing children with 22q11.2 deletion syndrome.

This review aimed to update the clinical practice guidelines for managing children and adolescents with 22q11.2 deletion syndrome (22q11.2DS).

Protocol for a Prospective Observational Study of Revision Palatoplasty Versus Pharyngoplasty for Treatment of Velopharyngeal Insufficiency Following Cleft Palate Repair.

Objective: To present the design and methodology for an actively enrolling comparative effectiveness study of revision palatoplasty versus pharyngoplasty for the treatment of velopharyngeal insufficiency (VPI).

Design: Prospective observational multicenter study.

Setting: Twelve hospitals across the United States and Canada.

Cleft Palate Repair Postoperative Management: Current Practices in the United States.

Objective: To describe current postoperative management practices following cleft palate repair.

Design: A survey was administered to cleft surgeons to collect information on their demographic characteristics, surgical training, surgical practice, and postoperative management preferences.

Setting: Eighteen tertiary referral hospitals across the United States.

Breeding Thin-Billed Prions Use Marine Habitats Ranging from Inshore to Distant Antarctic Waters.

Pelagic seabirds cover large distances efficiently and thus may reach a variety of marine habitats during breeding. Previous studies using stable isotope data and geolocators suggested that Thin-billed Prions breeding in the Falkland Islands in the Southwest Atlantic may forage in temperate waters over the Patagonian Shelf or cross the Drake Passage to forage in Antarctic waters south of the Polar Front. We deployed miniature GPS dataloggers to track Thin-billed prions in the Falkland Islands during incubation (3 seasons) and chick-rearing (2 seasons).

Potential for redistribution of post-moult habitat for Eudyptes penguins in the Southern Ocean under future climate conditions.

Anthropogenic climate change is resulting in spatial redistributions of many species. We assessed the potential effects of climate change on an abundant and widely distributed group of diving birds, Eudyptes penguins, which are the main avian consumers in the Southern Ocean in terms of biomass consumption. Despite their abundance, several of these species have undergone population declines over the past century, potentially due to changing oceanography and prey availability over the important winter months.

Fatty acid profiles of more than 470 marine species from the Southern Hemisphere.

Lipid and fatty acid datasets are commonly used to assess the nutritional composition of organisms, trophic ecology, and ecosystem dynamics. Lipids and their fatty acid constituents are essential nutrients to all forms of life because they contribute to biological processes such as energy flow and metabolism. Assessment of total lipids in tissues of organisms provides information on energy allocation and life-history strategies and can be an indicator of nutritional condition.

Assessment of the Velopharyngeal Mechanism at Rest and During Speech in Children With 22q11.2DS: A Cross-Sectional Study.

Objective: Velopharyngeal dysfunction (VPD) associated with 22q11.2 deletion syndrome (22q11.2DS) has a complex etiology.

Examining Risk of Speech-Language Disorders in Children With Cleft Lip.

Although it is well-established that children with cleft palate are at high risk for communication disorders, little is known about the speech-language profiles of children with cleft lip (with or without cleft alveolus), who do not have an overt cleft palate. The purpose of this study was to determine the prevalence of speech-language disorders in a consecutively evaluated group of children with cleft lip, with or without cleft alveolus (CL ± A) from a single cleft lip and palate center in the United States. We also explored the types of speech and language disorders in this cohort and examined the impact of co-occurring syndromes and other diagnoses (eg, submucous cleft palate).

Alveolar Backing in 3-Year-Old Children with and without Repaired Cleft Palate: Preliminary Findings Related to Cleft Type and History of Otitis Media.

Objective: The purpose of this preliminary study was to determine if cleft type and/or history of otitis media with effusion (OM) contribute to backing of /t/ and/or /s/ in young children with and without repaired cleft palate.

Method: Participants were 39 children (mean age=36 months, range 34 to 41). Ten children had repaired unilateral cleft lip and palate (CLP), nine had repaired cleft palate only (CP), twelve had no clefts but histories of OM, and eight were typically-developing (TD) without clefts or OM history.

Novel truncating variant in associated with cerebellar hypoplasia and velopharyngeal dysfunction.

-related neurodevelopmental disorder is a recently described intellectual disability syndrome often with speech difficulties. Here, we describe an individual with a heterozygous frameshift variant in (NM_182931.2:c.

Transcribing toddler vocalizations: comparison of a modified naturalistic listening approach with phonetic transcription.

Previous investigations have demonstrated that naturalistic listening in real time (NLRT) can be used reliability to assess prelinguistic vocalizations and is less time-consuming than phonetic transcription. The current investigation was performed to examine the correspondence of syllable and consonant information obtained using a modified naturalistic listening in real time (NLRT) methodology compared to broad phonetic transcription for 20 toddlers with repaired cleft palate. A forty-minute vocalization sample was obtained for each toddler.

Airway and Feeding Outcomes in Pierre Robin Sequence: A Comparison of Three Management Strategies.

Background: Controversy remains regarding optimal management of Pierre Robin sequence (PRS). The goal of this study was to compare airway and feeding outcomes in infants with PRS who underwent surgical intervention, specifically mandibular distraction osteogenesis (MDO) or tongue-lip adhesion (TLA), or who had conservative management (CM) without surgery.

Methods: All consecutive patients treated for PRS at a pediatric academic medical center, with at least one year follow-up, were included.

The cost of a meal: factors influencing prey profitability in Australian fur seals.

Knowledge of the factors shaping the foraging behaviour of species is central to understanding their ecosystem role and predicting their response to environmental variability. To maximise survival and reproduction, foraging strategies must balance the costs and benefits related to energy needed to pursue, manipulate, and consume prey with the nutritional reward obtained. While such information is vital for understanding how changes in prey assemblages may affect predators, determining these components is inherently difficult in cryptic predators.

Improving Psychosocial Risk Assessment and Service Provision for Craniofacial Team Patients: A Quality Improvement Project.

To improve psychosocial risk assessment and service provision for children with craniofacial conditions presenting for annual interdisciplinary team visits. Institute for Healthcare quality improvement model. U.