Montreal Cognitive Assessment (MoCA) use in general practice for the early detection of cognitive impairment: a feasibility study.

Background: GPs can detect cognitive impairment (CI) at a very early stage, allowing early support for people and their caregivers. The early onset of CI is between 50 years and 60 years. Currently, in France, the Mini-Mental State Examination (MMSE) remains the most used screening test, although it has a lower sensitivity and specificity than the Montreal Cognitive Assessment (MoCA) for detecting mild CI, taking an average of 15 minutes to complete.

Medical tourism for late abortion: Women's profile and circumstances. A quantitative study among women who travelled within Europe for late abortion.

Background: In France, women seeking abortion must do so before the maximum legal limit of 12 weeks of pregnancy (14 Gestational Weeks). Women seeking abortion after the 12-week limit tend to travel to the Netherlands, where the maximum legal limit is 22 weeks of pregnancy. The purpose of this study was to identify the profile and circumstances of women who travel from France to the Netherlands for a late abortion.

A face-to-face national congress experience during the COVID-19 pandemic: A report focussing on the risk of COVID-19 contamination.

Background: The Congress of the National College of Academic General Practitioners took place in France in June 2021. In total, 1300 participants were registered, provoking concerns about the risk of COVID-19 contamination.

Objectives: The study objective was to report participation in the first French face-to-face medical congress after restrictions due to COVID-19 and whether it resulted in COVID-19 contamination.

Relationship between training supervision and evolution of the density of GPs: a 3-year cohort study on French cities between 2018 and 2021.

Context: There is an uneven distribution of general practitioners (GPs) across territories of developed countries leading to inequalities in access to health care. Countries are implementing incentive or coercive policies depending on the characteristics of their health system. Several studies suggest that the location of practical training may influence the location of GPs' practices.

Anticoagulants' Safety and Effectiveness in General Practice: A Nationwide Prospective Cohort Study.

Purpose: Most real-world studies on anticoagulants have been based on health insurance databases or performed in secondary care. The aim of this study was to compare safety and effectiveness between patients treated with vitamin K antagonists (VKAs) and patients treated with direct oral anticoagulants (DOACs) in a general practice setting.

Methods: The CACAO study (Comparison of Accidents and their Circumstances with Oral Anticoagulants) is a multicenter prospective cohort study conducted among ambulatory patients taking an oral anticoagulant.

Anemia management in non-menopausal women in a primary care setting: a prospective evaluation of clinical practice.

Background: The study aimed to analyze anemia management in non-pregnant, and non-menopausal women aged from 18 to 50 years old, in a French primary care setting.

Methods: An observational descriptive prospective study was conducted between November 2018 and February 2019. Inclusion criteria were as followed: anemia diagnosed in women aged from 18 to 50, not pregnant and not menopausal.

How Doctors' Beliefs Influence Gynecological Health Care for Women Who Have Sex with Other Women.

Women who occasionally or regularly have sex with other women (WSW) are rarely identified in primary care. Although we know about their specific health needs, health care professionals still find it difficult to ask questions about sexual orientation (SO) and behaviors, and sometimes, patients may find them difficult to answer. The still remains a widespread attitude in health care.

Areas of improvement in anticoagulant safety. Data from the CACAO study, a cohort in general practice.

Background: Real-world studies on anticoagulants are mostly performed on health insurance databases, limited to reported events, and sometimes far from every-day issues in family practice. We assess the presence of data for safe monitoring of oral anticoagulants in general practice, and compare patients' knowledge of taking an anticoagulant between vitamin K antagonists (VKA) and direct anticoagulants (DOAC), and the general practitioner's perception of their adherence to anticoagulation.

Methods: The CACAO study is a national cohort study, conducted by general practitioners on ambulatory patients under oral anticoagulant.

[Involvement of the posterior eye segment in HLA B27(+) iridocyclitis. Incidence. Value of surgical treatment].

46 patients with the association of acute anterior uveitis and the presence of HLA B27 antigen were studied. Ankylosing spondylitis was found in 19 patients (41.3%).

[A case of multiple epitheliopathy associated with sub-retinal neovascularization].

Gass described the acute posterior multifocal placoid pigment epitheliopathy in 1968. The disturbance of visual function is generally temporary with subsequent recovery. We describe one case of peripapillary and macular neovascularization with decreasing visual acuity due to macular haemorrhage followed by a fibro-glial scar.

5-Methylcytosine in Chlorelle pyrenoidosa DNAs.

The presence of 5-methylcytosine in Chlorella pyrenoidosa (strain 211/8b) DNA's has been investigated by means of paper chromatography and thermal chromatography on hydroxyapatite. It has been shown that nuclear DNA contains 3.5 mol% 5-methylcytosine whereas no significant amount of this base can be detected in chloroplast DNA.

[Physico-chemical determination of the ploidy of the unicellular alga, Chlorella pyrenoidosa (strain 211/8b) (author's transl)].

The ploidy of the unicellular green alga Chlorella pyrenoidosa (strain 211/8b) has been determined by means of renaturation kinetics. The nuclear DNA is made up from fast, intermediate and slow renaturing sequences, which represent respectively about 5, 15 and 80% of the DNA. These observations are consistent with the findings in other eukaryotic nuclear DNAs.

The chloroplastic DNA of Chlorella pyrenoidosa (Emerson strain): heterogeneity and complexity.

The heterogeneity and the complexity of Emerson strain Chlorella pyrenoidosa chloroplastic DNA have been investigated by means of thermal denaturation and renaturation kinetics, and the results have been compared with those of the strain 211/8b of the same alga. The thermal denaturation properties are very close to those of the other strain: the Tm of 65 degrees C in 0.1 standard saline citrate, the maximal hyperchromicity of 41%, and the dispersion coefficent delta 2/3 of 6.

[Action of 8-azaguanine on cellular division of Chlorella pyrenoidosa : I. Selective inhibition of nuclear DNA synthesis].

Synchronized Chlorella cell cultures were supplemented with 8-azaguanine at different times in their life-cycle. The number of cells obtained after one cycle depended on the time at which the analogue was added to the cultures. The results suggest that, during one cycle, the successive cellular divisions are controlled by a specific "stimulus".