Hamartoma of hypothalamus presented as precocious puberty and epilepsy in a 10-year-old girl.

Background: Hamartoma of the hypothalamus represents a well-known but rare cause of central precocious puberty and gelastic epilepsy. Due to the delicate site in which a tumor is located, surgery is often difficult and associated with considerable risks.

Case Presentation: 10-Year old girl presented with early and regular menstruation at the age of 1 year each cycle lasted for 3 days.

Estimation of apolipoprotein A in early onset ST-segment elevation myocardial infarction.

Aims: The role of apolipoprotein A in early onset ST-segment elevation myocardial infarction is not clear. This study sought to assess the apolipoprotein A in cohort of patients diagnosed with early onset acute ST-segment elevation myocardial infarction and to corelate it with major traditional cardiovascular risk factors.

Methods: A total of 50 such patients and 40 age and sex-matched healthy controls, both aged less than 50 years with their baseline demographic, clinical characteristics and cardiovascular risk factors were studied.