Retrospective study of the relative frequency of cattle respiratory disease pathogens in clinical laboratory samples submitted by UK veterinary practices.

Background: The objective of this study was to explore the relative frequency and seasonality of bovine respiratory pathogens in the UK, based on clinical case submission for laboratory PCR testing.

Methods: This study used retrospective data generated by a central Scotland laboratory using 407 clinical (pooled) samples collected by 95 veterinary practices located throughout the UK between November 2020 and September 2022. Statistical analyses were performed using descriptive spatial analysis (choropleth maps), chi-squared analysis, Poisson and logistic regression modelling.

Mannheimia haemolytica serovars associated with respiratory disease in cattle in Great Britain.

Background: Mannheimia haemolytica is commonly associated with respiratory disease in cattle worldwide as a cause of fibrinous pneumonia, bronchopneumonia and pleuritis. M. haemolytica is further subdivided into 12 serovars, however not all are considered to be pathogenic in cattle.

Use of thoracic ultrasound on Scottish dairy cattle farms to support the diagnosis and treatment of bovine respiratory disease in calves.

Background: Bovine respiratory disease (BRD) is common in cattle youngstock on UK dairy farms. The current diagnostic methods lack sensitivity and specificity. Thoracic ultrasound (TUS) is a relatively new BRD diagnostic tool with increased accuracy.

What features on intraoperative cholangiogram predict endoscopic retrograde cholangiopancreatography outcome in patients post cholecystectomy?

Background: Endoscopic retrograde cholangiopancreatography (ERCP) is a procedure performed to remove bile duct stones. Intraoperative cholangiography (IOC) is often performed at the time of cholecystectomy to determine the presence of intraductal stones. However, many of the ERCP procedures performed for this indication fail to find any intraductal stones.

Lymphoma of the prostate treated with radiotherapy.

Primary prostatic lymphoma is a rare disease. We report a 73-year-old man who initially presented with features of bladder outflow obstruction. Histology revealed non-Hodgkin's lymphoma.

Peripheral arterial embolism. A 20 year review.

Two hundred and forty eight peripheral arterial emboli occurring in 221 patients during a period of 20 years have been retrospectively reviewed. Best results are seen following early surgery with the balloon catheter but, in the clinical absence of tissue necrosis, late embolectomy is worthwhile. Atrial fibrillation and post-myocardial thrombus are the major sources of emboli, but tumour and septic emboli do occur and histological and bacteriological examination of retrieved material is essential.

Palliative percutaneous transhepatic drainage for inoperable obstructive jaundice.

A technique of percutaneous transhepatic drainage under local anaesthesia is described for the relief of intractable pruritus in patients with obstructive jaundice due to inoperable carcinoma. After standard percutaneous transhepatic cholangiography a polyethylene catheter is introduced into one of the large dilated bile ducts and left in situ, thereby establishing external retrograde biliary drainage. The technique has been used successfully in 6 cases with reduction in serum bilirubin levels and relief of pruritus.

Contract cholangiography.

Clinical, operative, and conventional radiological criteria may provide insufficient indications for exploration of the common bile duct. The technique of contact cholangiography improves the radiographic definition, especially in the obese, and has resulted in more positive choledochotomies and in fewer negative explorations.

Randomized multicentre trial of oral bowel preparation and antimicrobials for elective colorectal operations.

A study of 120 patients undergoing elective colorectal operations has investigated the effect of adding oral neomycin and metronidazole to bowel preparation in a double-blind randomized controlled trial. Comparisons have also been made between a standard mechanical preparation and the use of an elemental diet. The addition of neomycin and metronidazole to bowel preparation significantly reduced the rate of wound sepsis (P less than 0.

Topical thrombin and control of wound haematoma.

The frequency of wound haematoma was investigated in 45 prophylactically heparinised patients undergoing abdominal surgery. Thrombin was applied locally to the wound in 15 patients, and in these patients wound haematoma was significantly less common than in the controls.

The effect of surgical biopsy on the cell production rate of a murine tumour.

The rate of cell production of a mammary adenocarcinoma following surgical biopsy has been investigated using vincristine sulphate as a metaphase arrest agent. Small implants of the tumour were implanted into the inguinal region of young mice of both sexes and were seen to have a constant rate of cell production both between different tumour generations and during tumour growth. Such a constant rate of tumour cell production provides an extremely useful model for exploring the effects of surgical biopsy.