Standard and modified administrations of the Iowa Tests of Basic Skills with learning disabled students.

The purpose of this study was to investigate the performance of junior high school learning disabled students on standard and modified administrations of selected subtests from the Iowa Tests of Basic Skills. No significant differences were noted for correlations between types of administration and teachers' ratings on any of the subtest comparisons. Grade placements for Vocabulary and Reading Comprehension using the modified administration were significantly higher than those using the standard administration and more closely aligned with teachers' ratings.

Adipose tissue thymidine kinase activity in man.

Thymidine kinase activity was studied during human adipose tissue development. Adipose tissue was obtained from the groin in 81 persons, aged 7 wk through 60 yr. None had a metabolic or growth disorder.

Medication compliance in children with asthma.

The aim of the study was to determine whether self-management skills, when taught to asthmatic children and their parents, would improve medication compliance. The latter was assessed by a variety of procedures including serum theophylline levels, pill counts by parents, and self-monitoring measures. Results indicated a group receiving self-management training showed no greater gains in medication compliance, self-concept, or health locus of control than did a self-monitoring-only group.

Pentobarbital effects on plasma catecholamines: temperature, heart rate, and blood pressure.

The effects of intravenous pentobarbital were studied in dogs. Plasma pentobarbital concentrations were inversely related to epinephrine and norepinephrine concentrations. Plasma catecholamines appeared fully suppressed at pentobarbital levels greater than 25-30 micrograms/ml.

Pentobarbital anesthesia suppresses basal and 2-deoxy-D-glucose-stimulated plasma catecholamines.

Since pentobarbital anesthesia is known to attenuate certain autonomic reflexes, we tested whether pentobarbital would suppress both basal and stimulated levels of plasma catecholamines and whether a large stimulus might counterbalance this suspected suppression. In untrained dogs, sampled by venipuncture, pentobarbital (30 mg/kg iv) decreased the plasma concentration of epinephrine (E) from 146 +/- 9 to 38 +/- 8 (SE) pg/ml (n = 46) and norepinephrine (NE) from 276 +/- 13 to 91 +/- 10 pg/ml (both P less than 0.0005), suggesting that barbiturate anesthesia suppresses sympathetic outflow in these mildly stressed animals.

Growth and tissue abnormalities in young people with cyanotic congenital heart disease receiving systemic-pulmonary artery shunts.

The effects of systemic-pulmonary artery shunts on growth, body composition, and adipose tissue were studied in 29 children, aged 2 to 16 years, with cyanotic congenital heart disease. Of these, 16 received surgical shunts and 13 were unoperated. Postoperatively, all patients who received shunts were better oxygenated (systemic oxygen saturation 69 +/- 11% preoperatively and 84 +/- 4% postoperatively; mean +/- standard error of the mean) and were symptomatically improved.

Antibody dependent cytotoxicity of human colostrum phagocytes.

Monocytes and polymorphonuclear neutrophils of human colostrum were identified using cytochemical staining procedures. The ability of colostral phagocytes to function in antibody dependent cellular cytotoxicity was found to be satisfactory at high effector/target cells ratio (20:1) Colostral monocytes showed a diminished cytotoxicity when compared to monocytes of adult or neonatal peripheral blood at low effector/target cells ratio (1:1). This could be due to the extensive fat ingestion by these cells or other inhibitory factors found in colostrum.

Norepinephrine-stimulated lipolysis in acute and chronic hypoxemia.

The effects of acute and chronic hypoxemia on norepinephrine-stimulated lipolysis were studied in dogs. Right-to-left shunts were created in experimental dogs to render them chronically hypoxemic (PaO2 37-55 torr). Control animals received sham operations (PaO2 greater than 70 torr).

Results of intraventricular baffle procedure for ventricular septal defect and double outlet right ventricle or d-transposition of the great arteries.

Thirty patients with ventricular septal defect and d-transposition of the great arteries or double outlet right ventricle underwent placement of an intraventricular baffle to achieve physiologic correction. Eighteen of these patients also required an external conduit to establish continuity between the right ventricle and the pulmonary artery. There was an overall 22 percent early mortality rate, although the rate was 63 percent in patients who weighed less than 10 kg.

Early heart failure as a cause of growth and tissue disorders in children with congenital heart disease.

Height, weight, total body fat, lean body mass, size of fat cells and total number of lipid-containing fat cells were compared in two groups of children, ages 2-6 years, with congenital heart disease. Twelve children who developed heart failure in infancy made up one group and 14 asymptomatic patients made up the other. No patient was cyanotic or had undergone surgical repair.

Stress hyperglycemia and the adrenergic regulation of pancreatic hormones in hypoxia.

Stress hyperglycemia occurs in normal and chronically hypoxemic dogs when PaO2's are acutely lowered below 30 torr. Several factors are thought to contribute to the rise in blood glucose. The initial fall in PaO2 activates the sympathetic nervous system, stimulating alpha and beta adrenergic receptors.

Partial purification of a specific antigen of Treponema hyodysenteriae.

A specific antigen of pathogenic Treponema hyodysenteriae was extracted from lyophilized cells of isolant B169 with hot phenol-water, isolated, and semipurified by starch block electrophoresis.

Hyperglucagonemia and alpha-adrenergic receptor in acute hypoxia.

The plasma immunoreactive glucagon (IRG) response to hypoxia was studied in puppies. Three groups of paired experiments were performed. In group I, 8% O2:92% N2 ventilation (PaO2 20--30 torr) produced a rise in plasma IRG and glucose as well as hypotension and bradycardia.

Immunity to Swine dysentery in recovered pigs.

The immune status of 29 pigs recovered from swine dysentery (SD) was evaluated after reexposure to Treponema hyodysenteriae. Pigs which had recovered from SD and remained asymptomatic for 4 to 6, 9 to 13, and 16 to 17 weeks after initial inoculation were reexposed to 1.5 X 10(9) viable cells of T hyodysenteriae per pig.

Serotypes of beta-hemolytic Treponema hyodysenteriae.

Cultures form 13 isolates of pathogenic, beta-hemolytic Treponema hyodysenteriae from 11 geographically separate outbreaks and 2 experimentally induced cases of swine dysentery were lyophilized and extracted with hot phenol-water. The resulting water phases were examined serologically with antisera produced in rabbits against whole-cell bacterins of the 13 isolates for evidence of antigenic classes within the species. Water-phase antigens gave precipitin reactions with homologous antisera.

An important complication of Hancock mitral valve replacement in children.

Nine children ages 2--15 years have undergone mitral valve replacement (MVR) with Hancock porcine heterograft valves for severe mitral insufficiency. The etiology of the mitral valve disease was rheumatic in two patients, and congenital in seven. Porcine valve sizes ranged from 19--31 mm.

Glucose-induced insulin release during acute and chronic hypoxia.

Glucose-induced insulin release was studied in young dogs during acute and chronic hypoxia, alone and in combination. Six experimental animals were rendered chronically hypoxic (PaO2, 43.4 +/- 0.