Extra-facial melasma is a common skin condition with unique clinical features and potential causes, impacting various populations.
A study involving 90 participants compared extra-facial melasma patients with healthy volunteers, assessing clinical characteristics and conducting biopsies to analyze skin differences.
Findings indicated that the melasma group was predominantly older women, often post-menopausal, with a notable family history, while histopathological analysis showed increased melanin density and signs of skin damage, although the number of melanocytes did not differ significantly between the groups.