How reliable are ADC measurements? A phantom and clinical study of cervical lymph nodes.

Objective: To assess the reliability of ADC measurements in vitro and in cervical lymph nodes of healthy volunteers.

Methods: We used a GE 1.5 T MRI scanner and a first ice-water phantom according to recommendations released by the Quantitative Imaging Biomarker Alliance (QIBA) for assessing ADC against reference values.