Aim: To study long-term sequelae in children with Guillain-Barré syndrome (GBS).
Method: This was a prospective observational study with children from two French tertiary centres. Data were from clinical and several standardized scales or questionnaires.
Background: Craniopharyngioma is a rare condition in children, but it is the most frequent tumor that occurs in the hypothalamic pituitary region. Chemical meningitis has been described as an uncommon postoperative complication, but no chemical meningitis due to a spontaneous rupture leading to craniopharyngioma diagnosis in children has been reported.
Case Presentation: This is a case of a 13-year-old boy presenting with fever, vomiting and headache for two days.
Introduction: Neuronal Ceroid Lipofuscinosis type 2 (CLN2) is a neurodegenerative lysosomal disease which leads to early dementia and death without treatment. The recently available therapy consists of intracerebroventricular enzyme substitution: cerliponase alfa. In this report, we describe the evolution of the first French children treated with cerliponase alfa.
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