High SARS-CoV-2 infection rates and viral loads in community-dwelling individuals from rural indigenous and mestizo communities from the Andes during the first wave of the COVID-19 pandemic in Ecuador.

Background: Neglected indigenous groups and underserved rural populations in Latin America are highly vulnerable to COVID-19 due to poor health infrastructure and limited access to SARS-CoV-2 diagnosis. The Andean region in Ecuador includes a large number of isolated rural mestizo and indigenous communities living under poverty conditions.

Objective: We herein present a retrospective analysis of the surveillance SARS-CoV-2 testing in community-dwelling populations from four provinces in the Ecuadorian Andes, carried out during the first weeks after the national lockdown was lifted in June 2020.

Quantum walks on a programmable two-dimensional 62-qubit superconducting processor.

Quantum walks are the quantum mechanical analog of classical random walks and an extremely powerful tool in quantum simulations, quantum search algorithms, and even for universal quantum computing. In our work, we have designed and fabricated an 8-by-8 two-dimensional square superconducting qubit array composed of 62 functional qubits. We used this device to demonstrate high-fidelity single- and two-particle quantum walks.

Chimera Time-Crystalline Order in Quantum Spin Networks.

Symmetries are well known to have had a profound role in our understanding of nature and are a critical design concept for the realization of advanced technologies. In fact, many symmetry-broken states associated with different phases of matter appear in a variety of quantum technology applications. Such symmetries are normally broken in spatial dimension, however, they can also be broken temporally leading to the concept of discrete time symmetries and their associated crystals.

Rare-Earth-Mediated Optomechanical System in the Reversed Dissipation Regime.

Strain-mediated interaction between phonons and telecom photons is demonstrated using excited states of erbium ions embedded in a mechanical resonator. Owing to the extremely long-lived nature of rare-earth ions, the dissipation rate of the optical resonance falls below that of the mechanical one. Thus, a "reversed dissipation regime" is achieved in the optical frequency region.

Ergodic-Localized Junctions in a Periodically Driven Spin Chain.

We report the analog simulation of an ergodic-localized junction by using an array of 12 coupled superconducting qubits. To perform the simulation, we fabricated a superconducting quantum processor that is divided into two domains: one is a driven domain representing an ergodic system, while the second is localized under the effect of disorder. Because of the overlap between localized and delocalized states, for a small disorder there is a proximity effect and localization is destroyed.

Simulating complex quantum networks with time crystals.

Crystals arise as the result of the breaking of a spatial translation symmetry. Similarly, translation symmetries can also be broken in time so that discrete time crystals appear. Here, we introduce a method to describe, characterize, and explore the physical phenomena related to this phase of matter using tools from graph theory.

The association between antidepressant treatment and brain connectivity in two double-blind, placebo-controlled clinical trials: a treatment mechanism study.

Background: Antidepressant medications offer an effective treatment for depression, yet nearly 50% of patients either do not respond or have side-effects rendering them unable to continue the course of treatment. Mechanistic studies might help advance the pharmacology of depression by identifying pathways through which treatments exert their effects. Toward this goal, we aimed to identify the effects of antidepressant treatment on neural connectivity, the relationship with symptom improvement, and to test whether these effects were reproducible across two studies.

Spectroscopic signatures of localization with interacting photons in superconducting qubits.

Quantized eigenenergies and their associated wave functions provide extensive information for predicting the physics of quantum many-body systems. Using a chain of nine superconducting qubits, we implement a technique for resolving the energy levels of interacting photons. We benchmark this method by capturing the main features of the intricate energy spectrum predicted for two-dimensional electrons in a magnetic field-the Hofstadter butterfly.

Publisher's Note: Driven Open Quantum Systems and Floquet Stroboscopic Dynamics [Phys. Rev. Lett. 117, 250401 (2016)].

This corrects the article DOI: 10.1103/PhysRevLett.117.

Driven Open Quantum Systems and Floquet Stroboscopic Dynamics.

We provide an analytic solution to the problem of system-bath dynamics under the effect of high-frequency driving that has applications in a large class of settings, such as driven-dissipative many-body systems. Our method relies on discrete symmetries of the system-bath Hamiltonian and provides the time evolution operator of the full system, including bath degrees of freedom, without weak-coupling or Markovian assumptions. An interpretation of the solution in terms of the stroboscopic evolution of a family of observables under the influence of an effective static Hamiltonian is proposed, which constitutes a flexible simulation procedure of nontrivial Hamiltonians.

Topological Pumping of Photons in Nonlinear Resonator Arrays.

We show how to implement topological or Thouless pumping of interacting photons in one-dimensional nonlinear resonator arrays by simply modulating the frequency of the resonators periodically in space and time. The interplay between the interactions and the adiabatic modulations enables robust transport of Fock states with few photons per site. We analyze the transport mechanism via an effective analytic model and study its topological properties and its protection to noise.

Semiclassical bifurcations and topological phase transitions in a one-dimensional lattice of coupled Lipkin-Meshkov-Glick models.

In this work we study a one-dimensional lattice of Lipkin-Meshkov-Glick models with alternating couplings between nearest-neighbors sites, which resembles the Su-Schrieffer-Heeger model. Typical properties of the underlying models are present in our semiclassical-topological hybrid system, allowing us to investigate an interplay between semiclassical bifurcations at mean-field level and topological phases. Our results show that bifurcations of the energy landscape lead to diverse ordered quantum phases.

Quantum signatures of chimera states.

Chimera states are complex spatiotemporal patterns in networks of identical oscillators, characterized by the coexistence of synchronized and desynchronized dynamics. Here we propose to extend the phenomenon of chimera states to the quantum regime, and uncover intriguing quantum signatures of these states. We calculate the quantum fluctuations about semiclassical trajectories and demonstrate that chimera states in the quantum regime can be characterized by bosonic squeezing, weighted quantum correlations, and measures of mutual information.

Quantum phase transitions in networks of Lipkin-Meshkov-Glick models.

We study the quantum critical behavior of networks consisting of Lipkin-Meshkov-Glick models with an anisotropic ferromagnetic coupling. We focus on the low-energy properties of the system within a mean-field approach and the quantum corrections around the mean-field solution. Our results show that the weak-coupling regime corresponds to the paramagnetic phase when the local field dominates the dynamics, but the local anisotropy leads to the existence of an exponentially degenerate ground state.

Quantum criticality and dynamical instability in the kicked-top model.

We investigate precursors of critical behavior in the quasienergy spectrum due to the dynamical instability in the kicked top. Using a semiclassical approach, we analytically obtain a logarithmic divergence in the density of states, which is analogous to a continuous excited state quantum phase transition in undriven systems. We propose a protocol to observe the cusp behavior of the magnetization close to the critical quasienergy.

ac-Driven quantum phase transition in the Lipkin-Meshkov-Glick model.

We establish a set of nonequilibrium quantum phase transitions in the Lipkin-Meshkov-Glick model under monochromatic modulation of the interparticle interaction. We show that the external driving induces a rich phase diagram that characterizes the multistability in the system. Interestingly, the number of stable configurations can be tuned by increasing the amplitude of the driving field.

Nonequilibrium quantum phase transitions in the Dicke model.

We establish a set of nonequilibrium quantum phase transitions in the Dicke model by considering a monochromatic nonadiabatic modulation of the atom-field coupling. For weak driving the system exhibits a set of sidebands which allow the circumvention of the no-go theorem which otherwise forbids the occurrence of superradiant phase transitions. At strong driving we show that the system exhibits a rich multistable structure and exhibits both first- and second-order nonequilibrium quantum phase transitions.