Cryoanalgesia for Pain Management After Pectus Excavatum Repair (COPPER) in Adolescents: A Randomized Controlled Trial.

Background: Patients undergoing Pectus Excavatum repair with the minimally invasive approach frequently report severe postoperative pain. The goal of the study is to determine the superiority of cryoanalgesia compared to standard of care for return to normal quality of life.

Methods: A randomized, active controlled, parallel groups trial (category IIb medical device) was designed for patients undergoing pectus excavatum repair.

Exploring the applicability of a lesion segmentation method on [F]fluorothymidine PET/CT images in diffuse large B-cell lymphoma.

Background And Purpose: The determination of the total metabolic tumour volume based on [F]fluorothymidine ([F]FLT) PET/CT images in diffuse large B-cell lymphoma has a potential clinical value for detecting early relapse in this type of heterogeneous lymphoproliferative tumours. Tumour segmentation is a key step in this process. For this purpose, our objective was to determine a segmentation threshold of [F]FLT PET/CT images, based on a reference tissue uptake, on a cohort of patients with diffuse large B-cell lymphoma (DLBCL) that have been scanned at different stages of the treatment.

[Desmoplastic round cell tumor].

Desmoplastic small round cell tumor is a rare and very aggressive neoplasm that belongs to the family of "small round blue cell tumors". It has a higher incidence in males in the second decade of life. It is due to translocation t(11;22) (p13;q12).

Prospective study on the clinical relevance of F-DOPA positron emission tomography/computed tomography in patients with medullary thyroid carcinoma.

Purpose: F-DOPA Positron Emission Tomography/Computed Tomography (F-DOPA PET/CT) is a sensitive functional imaging method (65-75%) for detecting disease localization in medullary thyroid cancer (MTC). We aimed: (i) to assess the clinical usefulness of F-DOPA PET/CT in patients with MTC and elevated calcitonin (Ctn) and CEA levels and, (ii) to evaluate changes in disease management secondary to the findings encountered with this methodology.

Methods: Thirty-six patients with MTC and Ctn levels ≥150 pg/ml were prospectively included.

[18F-fluorothymidine preclinical study in non-human primate. Dosimetry and biodistribution].

Positron emission tomography-computed tomography (PET-CT) is part of the new diagnostic and therapeutic algorithms for Hodgkin lymphoma. PET-CT is a valuable tool for the assessment of treatment response and prognosis, both by means of interim PET-CT with 2-[18F]fluoro-2-deoxy-D-glucose ([18F]FDG) as well as end of treatment (EOT) PET-CT. Given the low specificity of [18F]FDG for the diffuse large B cell lymphoma (DLBCL), there is an emerging need for a more specific radiopharmaceutical agent.

Surface Diffusion Control Enables Tailored-Aspect-Ratio Nanostructures in Area-Selective Atomic Layer Deposition.

Area-selective atomic layer deposition is a key technology for modern microelectronics as it eliminates alignment errors inherent to conventional approaches by enabling material deposition only in specific areas. Typically, the selectivity originates from surface modifications of the substrate that allow or block precursor adsorption. The control of the deposition process currently remains a major challenge as the selectivity of the no-growth areas is lost quickly.

Neurological Complications and Noninvasive Multimodal Neuromonitoring in Critically Ill Mechanically Ventilated COVID-19 Patients.

The incidence and the clinical presentation of neurological manifestations of coronavirus disease-2019 (COVID-19) remain unclear. No data regarding the use of neuromonitoring tools in this group of patients are available. This is a retrospective study of prospectively collected data.

Tailoring the protonic conductivity of porous yttria-stabilized zirconia thin films by surface modification.

Porous yttria-stabilized zirconia (YSZ) thin films were prepared by pulsed laser deposition to investigate the influence of specific surface area on the electronic, oxygen ion, and protonic transport properties. Electrochemical impedance spectroscopy was carried out as a function of temperature, oxygen activity and humidity of the surrounding atmosphere. At high humidity, protons on the surface of the porous YSZ thin films lead to increased conductivity, even for temperatures up to 700 °C.

Thermal stability, electrochemical and structural characterization of hydrothermally synthesised cobalt ferrite (CoFeO).

Monophasic nano-crystalline CoFeO (CFO) nanoparticles of high purity have been synthesised through a low temperature hydrothermal route, which does not involve hazardous chemicals, or conditions. The easy, green procedure involves a hydrothermal treatment at 135 °C of an aqueous suspension of the oxalate salts of the precursors. No further purification or annealing procedure was necessary to obtain the crystalline nano-structured oxide.

Recent Advancement and Clinical Implications of 18FDG-PET in Parkinson's Disease, Atypical Parkinsonisms, and Other Movement Disorders.

Purpose Of Review: The molecular imaging field has been very instrumental in identifying the multiple network interactions that compose the human brain. The cerebral glucose metabolism is associated with neural function. 18F-fluoro-deoxyglucose-PET (FDG-PET) studies reflect brain metabolism in a pattern-specific manner.

Radionecrosis versus disease progression in brain metastasis. Value of (18)F-DOPA PET/CT/MRI.

The use of (18)F-DOPA PET/CT with magnetic resonance imaging fusion and the use of visual methods and quantitative analysis helps to differentiate between changes post-radiosurgery vs. suspicion of disease progression in a patient with brain metastases from melanoma, thus facilitating taking early surgical action.

The importance of personality and parental styles on optimism in adolescents.

Some studies have suggested that personality factors are important to optimism development. Others have emphasized that family relations are relevant variables to optimism. This study aimed to evaluate the importance of parenting styles to optimism controlling for the variance accounted for by personality factors.