Publications by authors named "Bastian G Selman"
Article Synopsis
- - Sunscreen contains UV filters designed to protect skin from sunlight, but there are concerns about their toxicity and endocrine-disrupting effects.
- - A study using the ToxCast/Tox21 database evaluated six common UV filters and found that they generally exhibit low potency and mostly affect liver and kidney pathways, with weak endocrine activity.
- - For most of these filters, human plasma concentrations are significantly lower than levels that show biological effects in lab tests, suggesting minimal risk of toxicity or endocrine disruption in humans.
Additional non-animal methods are urgently needed to meet regulatory and animal welfare goals. TTC is a broadly used risk assessment tool. TTC based on external dose has limited utility for multi-route exposure and some types of structure activity relationship assessments.
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