The powerful synergistic effect of spiramycin/propolis loaded chitosan/alginate nanoparticles on acute murine toxoplasmosis.

The novel formula of spiramycin/propolis loaded chitosan (CS)/alginate (Alg) nanoparticles (NPs) was assessed for Toxoplasma gondii (T. gondii) treatment in comparison with the commercially available spiramycin regarding tissue penetration and blood brain barrier (BBB) passage. Swiss Albino mice were inoculated intraperitoneally by 2500 tachyzoites of the virulent T.

Egyptian Olea europaea leaves bioactive extract: Antibacterial and wound healing activity in normal and diabetic rats.

Background And Aim: activity evaluation of Egyptian leaves extracts, and healing activity assessment of the newly prepared ointment of leaves extracts mingled with Shea butter.

Experimental Procedure: Different extraction methods and solvents were used to extract Egyptian bioactive agent(s). Antibacterial, scavenging activity and evaluation of wound repair potentiality of extract were examined in normal and diabetic experimental rat models with induced circular excisions.