New Alpha-Amylase Inhibitory Metabolites from Pericarps of .

Two new benzophenones: garcimangophenones A () and B () and five formerly reported metabolites were purified from the pericarps EtOAc fraction of ((GM) Clusiaceae). Their structures were characterized by various spectral techniques and by comparing with the literature. The α-amylase inhibitory (AAI) potential of the isolated metabolites was assessed.

Chrysin attenuates estradiol-induced endometrial hyperplasia in rats via enhancing PPARα activity.

Endometrial hyperplasia (EH) is a complex condition that commonly affects women after menopause. Since the current available treatments for EH are mainly invasive, there is a need for developing new treatment modalities. Chrysin (Ch) is a dihydroxyflavone with numerous promising therapeutic potentials.

Cannabinoids for Treating Cardiovascular Disorders: Putting Together a Complex Puzzle.

Cannabinoids have been increasingly gaining attention for their therapeutic potential in treating various cardiovascular disorders. These disorders include myocardial infarction, hypertension, atherosclerosis, arrhythmias, and metabolic disorders. The aim of this review is to cover the main actions of cannabinoids on the cardiovascular system by examining the most recent advances in this field and major literature reviews.