Publications by authors named "Baskaran N"
Article Synopsis
- Autoinflammatory disorders are characterized by an exaggerated response of the innate immune system, primarily involving neutrophils and macrophages, and are differentiated from connective tissue diseases by the absence of anti-nuclear antibodies.
- Many of these disorders are linked to inherited genetic mutations and tend to manifest in childhood or early adulthood, though some, like VEXAS syndrome, highlight the potential for acquired mutations in adults.
- The review focuses on the cutaneous manifestations of various acquired autoinflammatory disorders, including adult-onset Still's disease and Schnitzler syndrome, which have significant diagnostic implications.
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory disorder affecting pilosebaceous units causing painful nodules, abscesses, and scarring. Despite global studies linking HS to metabolic syndrome, insights specific to Indian patients are limited.
Materials And Methods: This study aimed to describe the clinicodemographic characteristics and study frequency of metabolic syndrome in Indian HS patients.
Purpuric paradigm: Multiple purpuric lesions on palms.
Indian J Dermatol Venereol Leprol
November 2024
Article Synopsis
- The growing human population is causing more interactions with wildlife, leading to increased conflicts, particularly with Asian elephants in the Western Ghats of India.
- The study analyzed six years of human-elephant conflict (HEC) data alongside ecological factors to identify causes and patterns of crop damage, property damage, and human casualties.
- Key findings indicate that HEC is influenced by habitat conditions such as grass biomass and human activities, suggesting that reducing anthropogenic pressures could alleviate conflicts.
Article Synopsis
- The algorithmic patient preference predictor (PPP) aims to help make decisions for incapacitated patients when there are no advanced directives, highlighting both ethical challenges and practical issues in personalizing predictions.
- A review of studies found 68 using machine learning to predict patient-reported outcome measures (PROMs), with orthopedic and spinal surgeries being the most common focus; however, overall predictive performance was generally poor to moderate.
- Pre-event PROMs emerged as key predictors of post-event outcomes, indicating the need to integrate patient preferences into developing personalized PPP models, which currently lack adequate fairness assessments.
Article Synopsis
- Listeria monocytogenes is a harmful bacterium responsible for listeriosis, often found in ready-to-eat food, making its detection crucial for food safety.
- The study introduces an innovative, label-free electrochemical immunosensor using a polydopamine-modified zinc molybdate/MXene composite for rapid and effective detection of L. monocytogenes in various food products like milk and seafood.
- The immunosensor has shown high sensitivity with a low detection limit, good selectivity against other microbes, and impressive stability, suggesting its potential for broader applications in monitoring food safety against multiple pathogens.
Background The emergency department (ED) serves as the front line for emergency patient care, a unique limbo between the realms of generalist care and specialists and outpatient and inpatient care. As the trend of utilizing emergency healthcare services has escalated in the past 10 years, it becomes interesting to look at the patient characteristics of those who have utilized the ED. This analysis can guide the operation of impartial care for all ED patients to ensure equal access and discourage disparity based on the patient's sex.
View Article and Find Full Text PDFWater contamination is a serious environmental issue posing a significant global challenge. Roxarsone (ROX), a widely used anticoccidial drug is excreted in urine and feces, potentially disrupting natural habitats. Therefore, rapid and cost-effective ROX detection is essential.
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- The study investigates the effectiveness of large language models (LLMs) in incorporating patient values during critical medical decision-making for patients who can't make decisions due to incapacitation.
- Researchers simulated scenarios for 50 patients needing urgent medical decisions and assessed how well LLMs could extract treatment options and provide recommendations based on the patients' values.
- Results showed that LLMs accurately extracted treatment information 88% of the time and received good scores for their recommendations in terms of medical plausibility and alignment with patient values, especially when values were expressed in free-text narratives.
Linear and Annular Lupus Panniculitis of the Scalp with Annular Lupus Panniculitis of the Face in a Child.
Indian Dermatol Online J
November 2023
Linear and annular lupus panniculitis of the scalp is a rare form of lupus panniculitis recently reported in literature. It presents as linear or annular or arciform areas of nonscarring alopecia of the scalp with minimal surface changes. We report a 4-year-old Indian female child with arciform erythematous plaque over the forehead extending on the scalp with nonscarring alopecia with annular erythematous plaque over the cheek.
View Article and Find Full Text PDFObjective: This study aimed to describe the effect of the pandemic on epidemiologic trends and disparities in outcomes for patients hospitalized with acute hyperglycemic complications (AHC).
Methods: This was a retrospective study of the National Inpatient Sample (NIS) database from 2016 to 2020. The population included adults hospitalized with AHCs as a principal diagnosis using the Clinical Classifications Software Refined code.
We present a rare case of ocular diffuse large B-cell lymphoma (DLBCL) unveiled through Pars Plana Vitrectomy in a 74-year-old immunocompromised male, highlighting the surgical insight and multidisciplinary management required for similar cases. The patient's progressive vision impairment led to a Pars Plana Vitrectomy, which confirmed DLBCL through cytogenetic analysis. Initial intraocular rituximab treatment showed promise; however, the lymphoma's systemic progression necessitated a shift to more aggressive chemotherapy, underscored by pleural and pericardial effusions and central nervous system involvement.
View Article and Find Full Text PDFA man in his late 20s presented to the emergency department with sudden-onset abdominal pain. Urinalysis was significant for hematuria and slightly elevated creatinine. A computed tomography (CT) scan with IV contrast revealed bilateral renal infarcts, which was corroborated by a computed tomography angiogram (CTA).
View Article and Find Full Text PDFKaghaznagar and Sironcha Forest Divisions in the Deccan Plateau of India support large breeding colonies of critically endangered species of long-billed (LBV) and white-rumped (WRV) vultures. To assess their abundance and age-structure, that are important population parameters, they were surveyed every month at their breeding colonies; LBV at Palarapu cliff during 2010-2021 and Lakkameda cliff during 2015-2021, and WRV at Dechilpeta during 2014-2021. Breeding colonies of LBV supported a mean of 32 ± 1.
View Article and Find Full Text PDFBackground: Takotsubo cardiomyopathy (TCM) is classically associated with significant gender disparities, such that it is more prevalent in females, but the clinical outcomes are worse for male patients. The goal of this study was to assess contemporary gender disparities in clinical outcomes of TCM hospitalizations and to determine predictors of male in-hospital mortality.
Methods: This was a retrospective analysis involving adult hospitalizations for TCM in the U.
Acute lung injury following fentanyl overdose is an unusual presentation. Pulmonary edema has been associated with opioid and naloxone use. However, to our knowledge, there have been no previous reports of inhaled fentanyl-associated acute lung injury presenting with acute hypoxic respiratory failure secondary to severe acute respiratory distress syndrome.
View Article and Find Full Text PDFIn this study, a novel electrochemical sensor was created by fabricating a screen-printed carbon electrode with diamond nanoparticles (DNPs/SPCE). The successful development of the sensor enabled the specific detection of the anti-cancer drug flutamide (FLT). The DNPs/SPCE demonstrated excellent conductivity, remarkable electrocatalytic activity, and swift electron transfer, all of which contribute to the advantageous monitoring of FLT.
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