Serum anti-müllerian hormone levels in evaluation of chemotherapy effect on ovarian reserve in women with breast cancer. A follow-up study.

Objectives: To investigate the role of serum anti müllerian hormone (AMH) pre-chemotherapy treatment levels in prediction of post-chemotherapy effect on the ovarian reserve of women with breast cancer.

Methods: This cohort prospective study was carried out at the Biochemistry Department, College of Medicine, University of Baghdad and at the Oncology Clinic, Oncology Teaching Hospital, Baghdad, Iraq. It included 58 women with regular menstrual cycle (25-45 years) who were  newly diagnosed with breast cancer.

The role of anti-Mullerian hormone and inhibin B in the assessment of metformin therapy in women with polycystic ovarian syndrome.

Objectives: To evaluate the role of anti-Mullerian hormone (AMH) and inhibin B in the evaluation of the effectiveness of short- (3 months) and long-term (6 months or more) metformin therapy in Iraqi women with polycystic ovarian syndrome (PCOS).

Methods: This cross-sectional study was carried out at the Biochemistry Department, College of Medicine, University of Baghdad, Baghdad, Iraq from June 2010 to May 2011. It included 38 volunteers of women patients with PCOS, aged 18-38 years, who were classified into: Group I (GI, n=20); Group II included women in GI that were followed up after they were treated with metformin hydrochloride tablet 500 mg 3 times daily for 3 months; and GIII included 18 women that were already on metformin hydrochloride treatment 500 mg tablet 3 times daily for 6 months to 3 years.

Andropause phenomenon by measurement of serum free testosterone concentration in Iraqi healthy men. Age related study.

Objective: To investigate the andropause phenomenon in Iraqi healthy subjects by evaluating serum free testosterone (FT) concentrations in association with age.

Methods: This study was carried out at the Biochemistry Department, College of Medicine, University of Baghdad, between February 2012 and October 2012. This cross sectional control subject's study included 251 healthy Iraqi men with an age range of 20-82 years.

Role of growth hormone and insulin-like growth factor-I in hyperandrogenism and the severity of acne vulgaris in young males.

Objective: To evaluate the association of growth hormone (GH), and insulin-like growth factor-1(IGF-1) in the production of male sex hormones and the severity of acne in Iraqi male patients, and to assess their role in development of secondary hyperlipidemia in such patients.

Methods: We conducted this case-control study and single-center measurement of hormones and selected biochemical parameters in a cohort of volunteer males in the Department of Biochemistry College of Medicine, Baghdad University, and in the Dermatology Department, Baghdad Teaching Hospital, Iraq, from January 2010 to November 2010.

Results: The mean serum levels of GH and IGF-1 of severe acne patients were significantly increased when compared with mild-, moderate acne patients, and healthy controls (p=0.

The frequency of 21-alpha hydroxylase enzyme deficiency and related sex hormones in Iraqi healthy male subjects versus patients with acne vulgaris.

Objective: To find out the frequency of nonclassical congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency among Iraqi healthy male individuals versus male patients with acne vulgaris.

Methods: This case-control study and single-center examination of hormone levels in a cohort of volunteers was conducted in the Department of Dermatology, Baghdad Teaching Hospital, and in the Physiological Chemistry Department of the College of Medicine, Baghdad University, Baghdad, Iraq, from September 2007 to February 2008.

Results: The frequency of 21-hydroxylase enzyme deficiency in healthy male subjects was 1:43 (2.