RP-HPLC Method for the Determination and Quantification of Artesunate.

A simple, rapid and cost-effective reverse phase high-performance liquid chromatographic (RP-HPLC) method was developed for the quantification of artesunate. C18 Promosil (ODS, 150 × 4.6 mm, 5 μm) column was used as stationary phase to separate the drug.

Enhancement of solubility and dissolution profile of artesunate by employing solid dispersion approach: An in-vitro evaluation.

Current study was designed with an aim to improve the solubility and dissolution profile of artesunate by preparing solid dispersions through solvent evaporation and freeze-drying techniques using polyethylene glycol 4000 (PEG4000) as solubility enhancer. Developed formulations were characterized for FTIR, XRD, TGA and SEM. Maximum increase in solubility was attained by freeze-dried solid dispersions (FD F444) i.

Immunomodulatory, Cytotoxicity, and Antioxidant Activities of Roots of .

Aims: The study is conducted to evaluate the immunomodulatory, cytotoxicity, and antioxidant potential of (Rhamnaceae). Phytochemical analysis of revealed the presence of alkaloids, anthraquinone glycoside, cardiac glycoside, saponin, tannin, and flavonoids.

Methodology: The cytotoxicity of the plant was evaluated by brine shrimp lethality test.

Diuretic and serum electrolyte regulation potential of aqueous methanolic extract of Solanum surattense fruit validates its folkloric use in dysuria.

Background: Solanum surattense Burm. (Solanaceae) is traditionally used for management of various ailments. The study was conducted for provision of pharmacological justification for folkloric uses of Solanum surattense in the treatment of dysuria.