Publications by authors named "Bashar Asir"
Deep Brain Stimulation (DBS) in Treatment-Resistant Depression (TRD): Hope and Concern.
Adv Exp Med Biol
September 2024
Article Synopsis
- * It examines the neural networks involved in depression, the technical aspects of DBS, and reviews clinical trial outcomes while addressing safety and ethical issues.
- * Finally, the chapter proposes future research directions for DBS, highlighting innovations like closed-loop systems and machine-learning approaches to improve study designs and efficacy.
Article Synopsis
- Deep brain stimulation (DBS) targeting the medial forebrain bundle shows promise as a treatment for therapy-resistant depression, with effects lasting up to 5 years in some patients.
- The study tracked 10 patients, assessing improvements using the Montgomery-Åsberg Depression Rating Scale, with significant reductions in scores post-stimulation.
- Key recommendations for future studies include extending the sham stimulation phase and integrating functional imaging to better understand treatment effects.