Publications by authors named "Basha Ayele"
Article Synopsis
- Shigellosis is a major health issue in Ethiopia, particularly affecting young children, and is exacerbated by antimicrobial resistance due to misuse of antibiotics and poor hygiene.
- The study utilized whole genome sequencing (WGS) to examine Shigella sonnei strains in Addis Ababa, focusing on antibiotic resistance genes and plasmid types associated with these strains.
- Findings showed a variety of resistance genes and phenotypic resistance patterns, indicating significant genetic diversity in S. sonnei strains, which suggests the need for enhanced monitoring of antimicrobial resistance through WGS.
Prevalence and Antimicrobial-Resistant Features of Species in East Africa from 2015-2022: A Systematic Review and Meta-Analysis.
Interdiscip Perspect Infect Dis
September 2023
Background: Shigellosis is the most common cause of epidemic dysentery found worldwide, particularly in developing countries, where it causes infant diarrhea and mortality. The prevalence of species resistant to commonly used antimicrobial drugs has steadily increased. The purpose of this review is to describe the prevalence and antimicrobial resistance (AMR) characteristics of species in East Africa between 2015 and 2022.
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- Shigellosis is a significant public health issue in Ethiopia, especially affecting children under five, with high rates of antibiotic resistance reported.
- A study was conducted in Addis Ababa to analyze the antimicrobial characteristics of bacterial species from children with acute diarrhea, involving fecal sample collection and testing for antibiotic susceptibility.
- Results indicated a low prevalence of intestinal parasites but high resistance rates to common antibiotics like amoxicillin and erythromycin, raising concerns about treatment effectiveness and highlighting a significant public health challenge.