Publications by authors named "Basema K Balasiny"
Article Synopsis
- Scientists discovered a new type of nitrite reductase called YtfE, which has iron in it and helps with various functions in cells.
- YtfE increases nitrogen oxide (NO) production from nitrite, which can help protect the cells from stress.
- The studies showed that YtfE can change when nitrite is added, allowing it to release nitrogen oxide and be involved in protecting cells under stressful conditions.
The hybrid cluster protein, Hcp, contains a 4Fe-2S-2O iron-sulfur-oxygen cluster that is currently considered to be unique in biology. It protects various bacteria from nitrosative stress, but the mechanism is unknown. We demonstrate that the Escherichia coli Hcp is a high affinity nitric oxide (NO) reductase that is the major enzyme for reducing NO stoichiometrically to N2 O under physiologically relevant conditions.
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