Publications by authors named "Basel Ibrahim"

Article Synopsis
  • The study examines the immune response of CD4+ T helper cells in patients with atopic dermatitis (AD), focusing on pro-inflammatory cytokines and heat shock proteins.
  • It employs peripheral blood samples from AD patients and healthy controls, using immune activators to stimulate cytokine expression in T cells.
  • Findings indicate heightened levels of both Th1 and Th2 cytokines in AD patients, suggesting a complex immune profile that may help inform future treatments for atopic diseases.
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Given a spherical set of points, we consider the detection of cocircular subsets of the data. We distinguish great circles from small circles, and develop algorithms for detecting cocircularities of both types. The suggested approach is an extension of the Hough transform.

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Ethnopharmacological Relevance: Diabetea tea™ (DT) is an anti-diabetic alternative medicine in some Asian countries. The main constituent of DT is black tea originating from Camellia sinensis that is supplemented by 12 other medicinal plants. Black tea contains a large amount of the flavonoids catechins especially epigallocatechin gallate (EGCG) which has anti-inflammatory and antioxidative capacity.

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Sour cherry seed extract (SCE) was evaluated for its capacity to inhibit lipopolysaccharide-treated human peripheral blood T cells expressing tumor necrosis factor-alpha, and the chemokine interleukin-8. Both proteins are diagnostic biomarkers for inflammatory pathologies. Peripheral blood leukocytes from 11 rheumatoid arthritis (RA) patients and 8 healthy control subjects were co-cultured for 24h in lipopolysaccharide and the extract, then evaluated by flow cytometry for T cell activation and by enzyme-linked immunoassay for lymphocyte-associated heme oxygenase-1 (HO-1) expression.

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