Hepatitis-C Infection: Are we really committed to eliminate? Could it become the second Polio for Pakistan?

Pakistan's hepatitis C virus (HCV) burden is one of the highest in the world. Around eight million people live with HCV in Pakistan according to a National Hepatitis Survey. Most HCV-infected people are unaware of their infection status culminating in delayed diagnosis and treatment, progressing to end stage liver disease, cirrhosis, and hepatocellular carcinoma (HCC), thereby raising the disease load for a developing country with limited resources.

Safety of endoscopic N-Butyl-2 Cyanoacrylate injection for the treatment of bleeding gastric varices in children.

Objective: To determine the safety and efficacy of N-butyl 2-cyanoacrylate in bleeding gastric varices in children.

Methods: This retrospective observational study was conducted in the Department of Gastroenterology and Pediatric Surgery in Liaquat National Hospital Karachi between January 2010 and January 2017. Gastric fundal varices were obliterated in pediatric population with single shot of N-butyl-2 Cyanoacrylate 0.

Aortoenteric fistula - A fatal cause of gastrointestinal bleeding. Can it be missed? - A case report.

Gastrointestinal (GI) bleeding, is the life threating presentation of many diseases in emergency room. Aortoenteric fistula (AEF) is one of the rare causes of GI bleeding that can be fatal if not diagnosed and treated promptly. We present a case of a86 years old hypertensive male with the history of fresh bleeding per rectum, dizziness, fatigability and palpitation for last 12 hours who came to the emergency room in January 2015 He was stabilized and resuscitated.

Manifestation of hydatid cyst of liver with pancreatitis, cholangitis and jaundice: A case report.

Hydatid disease or echinococcosis, a systemic zoonosis is caused by Echinococcusgranulosus larvae. This is a common disease found all over the world, especially in the Mediterranean region. We report a 40 year old male with no known comorbids who came with complaints of fever with rigors and chills, right hypochondriac pain, and yellow discolouration of the sclera.

Severe haemolysis and renal failure precipitated by hepatitis E virus in G6PD Deficient patient: A case report.

Hepatitis E virus is the etiological agent for Hepatitis E infection, which is congruent to Hepatitis A infection. The clinical spectrum of the disease range from asymptomatic self-limiting disease which requires no treatment to life threatening fulminant liver disease in pregnancy, G6PD deficient and post-liver transplant patients, which necessitate urgent treatment. Similarly we are reporting a case of a 28 year old male with no previous known comorbids, who presented in emergency department with low grade fever, yellow discolouration of eyes and upper abdominal pain for last 5-6 days.

Safety of Trans-Nasal Percutaneous Endoscopic Gastrostomy Placement.

Objective: To evaluate the safety of trans-nasal percutaneous endoscopic gastrostomy (TPEG) placement for nutrition in patients where oral approach is not possible.

Study Design: Case-series.

Place And Duration Of Study: April 2010 to April 2016 in the Department of Gastroenterology at Liaquat National Hospital, Karachi.