A Multiomic Analysis of Chicken Serum Revealed the Modulation of Host Factors Due to Colonization and In-Water Supplementation of Eugenol Nanoemulsion.

is a foodborne pathogen that causes campylobacteriosis globally, affecting ~95 million people worldwide. Most infections involve consuming and/or handling improperly cooked poultry meat. To better understand chicken host factors modulated by colonization, we explored a novel LCMS-based multiomic technology using three experimental groups: (1) negative control, (2) positive control, and (3) eugenol nanoemulsion (EGNE) treatment (supplemented with 0.

Select Phytochemicals Reduce in Postharvest Poultry and Modulate the Virulence Attributes of .

Consumption or handling of poultry and poultry products contaminated with species are a leading cause of foodborne illness in humans. Current strategies employed to reduce in live chickens provide inconsistent results indicating the need for an alternative approach. This study investigated the efficacy of phytochemicals, namely, turmeric, curcumin, allyl sulfide, garlic oil, and ginger oil, to reduce in postharvest poultry and sought to delineate the underlying mechanisms of action.

Serotonin modulates Campylobacter jejuni physiology and invitro interaction with the gut epithelium.

Microbial endocrinology, which is the study of neurochemical-based host-microbe interaction, has demonstrated that neurochemicals affect bacterial pathogenicity. A variety of neurochemicals, including norepinephrine, were shown to enhance intestinal epithelial colonization by Campylobacter jejuni. Yet, little is known whether serotonin, an abundant neurochemical produced in the gut, affects the physiology of C.

Sodium Butyrate Reduces Enteritidis Infection of Chicken Enterocytes and Expression of Inflammatory Host Genes .

Enteritidis (SE) is a facultative intracellular pathogen that colonizes the chicken gut leading to contamination of carcasses during processing. A reduction in intestinal colonization by SE could result in reduced carcass contamination thereby reducing the risk of illnesses in humans. Short chain fatty acids such as butyrate are microbial metabolites produced in the gut that exert various beneficial effects.

Draft Genome Sequences of Campylobacter jejuni Strains Isolated from Poultry.

Four wild-type strains isolated from the cecal contents of broiler chickens were sequenced. The average genome size was 1,622,170 bp, with 1,667 to 1,761 coding sequences and 47 to 51 RNAs. Multiple genes encoding motility, intestinal colonization, toxin production, stress tolerance, and multidrug resistance were present in all the strains.

-Cinnamaldehyde, Eugenol and Carvacrol Reduce Biofilms and Modulate Expression of Select Genes and Proteins.

is the leading cause of human foodborne illness globally, and is strongly linked with the consumption of contaminated poultry products. Several studies have shown that can form sanitizer tolerant biofilm leading to product contamination, however, limited research has been conducted to develop effective control strategies against biofilms. This study investigated the efficacy of three generally recognized as safe status phytochemicals namely, -cinnamaldehyde (TC), eugenol (EG), or carvacrol (CR) in inhibiting biofilm formation and inactivating mature biofilm on common food contact surfaces at 20 and 37°C.

Edible Coatings Fortified With Carvacrol Reduce on Chicken Wingettes and Modulate Expression of Select Virulence Genes.

, a leading cause of foodborne disease in humans, associate primarily with consumption of contaminated poultry and poultry products. Intervention strategies aimed at reducing contamination on poultry products could significantly reduce infection in humans. This study evaluated the efficacy of gum arabic (GA) and chitosan (CH) fortified with carvacrol (CR) as an antimicrobial coating treatment for reducing on chicken wingettes.

Application of β-Resorcylic Acid as Potential Antimicrobial Feed Additive to Reduce Colonization in Broiler Chickens.

is one of the major foodborne pathogens that result in severe gastroenteritis in humans, primarily through consumption of contaminated poultry products. Chickens are the reservoir host of , where the pathogen colonizes the ceca, thereby leading to contamination of carcass during slaughter. A reduction in cecal colonization by would directly translate into reduced product contamination and risk of human infections.