Publications by authors named "Bas A Jongbloed"
Article Synopsis
- The study aimed to assess the relationship between MRI abnormalities in the brachial plexus and clinical weakness in conditions like multifocal motor neuropathy (MMN), Lewis-Sumner syndrome (LSS), and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).
- MRI abnormalities were found in 45% of patients; however, these abnormalities did not predict disease progression or treatment response.
- Asymmetrical MRI abnormalities were linked to MMN and LSS, while CIDP patients typically showed symmetrical abnormalities.
Objectives: To study disease mechanisms in multifocal motor neuropathy (MMN) with magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) of the median and ulnar nerves.
Methods: We enrolled ten MMN patients, ten patients with amyotrophic lateral sclerosis (ALS) and ten healthy controls (HCs). Patients underwent MRI (in a prone position) and nerve conduction studies.
Introduction: Differentiating multifocal motor neuropathy (MMN) from amyotrophic lateral sclerosis (ALS) is important, as MMN is a difficult, but treatable disorder.
Methods: We studied peripheral nerve imaging techniques in differentiating MMN from ALS by measuring the cross-sectional area (CSA) of the median and ulnar nerves in the forearms using high resolution ultrasound (HRUS) and MRI.
Results: HRUS CSA values of the median nerve in the forearm (P = 0.
Multifocal motor neuropathy (MMN) is a rare inflammatory neuropathy characterized by progressive, asymmetric distal limb weakness and conduction block (CB). Clinically MMN is a pure motor neuropathy, which as such can mimic motor neuron disease. GM1-specific IgM antibodies are present in the serum of approximately half of all MMN patients, and are thought to play a key role in the immune pathophysiology.
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