The prognostic role of cardiopulmonary exercise testing in obesity.

Aim: Poor cardiorespiratory fitness has been suggested to increase the risk of chronic diseases in obesity. We investigated the ability of key variables from cardiopulmonary exercise testing (CPET) to predict all-cause mortality in an obese cohort.

Methods: The sample included 469 participants of both sexes (mean age 40 ± 13 years) who underwent a CPET for clinical reasons between 1 March 2009 and 1 December 2023.

Potential Therapeutic Role of Respiratory Muscle Training in Dyspnea Management of Cancer Survivors: A Narrative Review.

Dyspnea is a disabling symptom presented in approximately half of all cancer survivors. From a clinical perspective, despite the availability of pharmacotherapies, evidence-based effective treatments are limited for relieving dyspnea in cancer survivors. Preliminary evidence supports the potential of respiratory muscle training to reduce dyspnea in cancer survivors, although large randomized controlled studies are warranted.

Cardiorespiratory Fitness and Incidence of Digestive System Cancers in Men.

Purpose: To assess the association between cardiorespiratory fitness (CRF) and incidence of digestive system cancers (DSCs) in men.

Methods: A prospective cohort of 4,540 men aged 55.2 ± 13.

Haemodynamic gain index and heart failure incidence- Prognostic and preventive value.

Aims: Heart failure (HF) is a non-curable, life-threatening condition, characterized by impaired haemodynamic function and poor survival. This study aimed to assess the association between haemodynamic gain index (HGI) and HF incidence in men.

Methods And Results: Exposure was HGI, [(HRpeak*SBPpeak) - (HRrest*SBPrest)]/(HRrest*SBPrest) measured from treadmill exercise testing in 5539 men aged 59 ± 11.

Dyslipidemia paradox: Analysis from the veterans exercise testing study.

Background: Dyslipidemia is a well-established cardiovascular disease (CVD) risk factor, although its association with mortality is less clear. This study aimed to assess the association between established dyslipidemia criteria [National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults [Adult Treatment Panel (ATP) III] and all-cause mortality in men.

Methods: Prospective cohort study of 1,479 men aged 59.

Non-exercise estimated cardiorespiratory fitness and cancer incidence: The NIH-AARP diet and health study.

Background: Non-exercise estimated cardiorespiratory fitness (NEE-CRF) has been shown to be associated with mortality, although its association with cancer incidence is unknown. The study aimed to assess the prospective association between NEE-CRF and cancer incidence in a large cohort of men and women.

Methods: The National Institutes of Health-American Association of Retired Persons diet and health study is a prospective cohort that included 402,548 participants aged 50-71 years who were free from cancer at baseline (1995-1996) (men (n = 238,835) and women (n = 163,713)) and were followed until December 31, 2015.

Could sarcopenia-related mortality in end-stage renal disease be underpinned by the number of hospitalizations and cardiovascular diseases?

Purpose: To investigate the association between sarcopenia with the number of all-cause mortality, hospitalizations, and cardiovascular diseases in patients with end-stage renal disease (ESRD).

Methods: 247 patients with ESRD (women, n = 97) (66.6 ± 3.

Poor handgrip strength determined clinically is associated with falls in older women.

Objectives: To assess the association between poor handgrip strength (HGS) determined by clinical criterion and incidence of falls in older women.

Methods: The cohort included 195 women (68.1±6.

Non-exercise estimated cardiorespiratory fitness and mortality from all-causes, cardiovascular disease, and cancer in the NIH-AARP diet and health study.

Aims: Impractical methods and relatively small cohort have limited the applications of non-exercise estimated cardiorespiratory fitness (NEE-CRF). This study aimed to assess the association between a pragmatic NEE-CRF method and mortality outcomes in a large prospective cohort.

Methods And Results: A total of 330 769 participants [men (n = 186 469) and women (n = 144 300)] aged 50-71 years from the NIH-AARP Diet and Health Study were assessed at baseline (1995-96) and prospectively followed until 31 December 2015 (14.

Physical Activity, Cardiorespiratory Fitness, and Population-Attributable Risk.

Objective: To determine population-attributable risk (PAR) and exposure impact number (EIN) for mortality associated with impaired cardiorespiratory fitness (CRF), physical inactivity, and other risk markers among veteran subjects.

Methods: The sample included 5890 male subjects (mean age 58±15) who underwent a maximal exercise test for clinical reasons between January 1, 1992, and December 31, 2014. All-cause mortality was the end point.

Long-term outcomes of metallic endobronchial stents in lung transplant recipients are not affected by bacterial colonization.

Objectives: We evaluated associations of endobronchial stenting with airway bacterial colonization, the antimicrobial resistance profile, hospitalizations for pneumonia and survival in lung transplant recipients.

Methods: This is a retrospective single-centre study of 582 recipients of lung transplant during 2002-2018. We compared outcomes of 57 patients (9.

Retracted: Facemasks in the COVID-19 era: A health hypothesis.

Many countries across the globe utilized medical and non-medical facemasks as non-pharmaceutical intervention for reducing the transmission and infectivity of coronavirus disease-2019 (COVID-19). Although, scientific evidence supporting facemasks' efficacy is lacking, adverse physiological, psychological and health effects are established. Is has been hypothesized that facemasks have compromised safety and efficacy profile and should be avoided from use.

Clinical Improvement and Effectiveness of Exercise-Based Pulmonary Rehabilitation in Patients With Idiopathic Pulmonary Fibrosis: A BRIEF ANALYTICAL REVIEW.

Background: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease associated with high mortality rates and poor clinical condition. Exercise-based pulmonary rehabilitation (EBPR) has been demonstrated to be effective in improving 6-min walk distance (6MWD), although the clinical improvement and effectiveness are less characterized. The current review examined the existing evidence of EBPR among patients with IPF and aimed to analyze the effect of EBPR on clinical improvement and effectiveness.

Hemodynamic gain index in women: A validation study.

Background: A previous study showed a strong and independent association between hemodynamic gain index (HGI) and all-cause mortality in a large cohort of men. The current study aimed to validate the association between HGI and all-cause mortality in a pilot cohort of women.

Methods: The cohort included 606 women aged 54.

The Etiology and Prognosis of Delayed Postoperative Leukocytosis in Lung Transplant Recipients.

Background: Leukocytosis (white blood cell count >12 000/µL) in the delayed postoperative period (4-7 days) after lung transplantation is due to diverse etiologies. We aimed to describe the etiologies of delayed postoperative leukocytosis in lung transplant recipients and to evaluate the association of leukocytosis causes with short-term survival.

Methods: A retrospective chart review of 274 lung transplantations performed in our institution during 2006 to 2013.

Cardiorespiratory fitness and cancer in men with cardiovascular disease: Analysis from the Veterans Exercise Testing Study.

Background: Cardiovascular disease and cancer share similar risk factors and are the leading causes of death worldwide. This study aimed to assess the association between cardiorespiratory fitness, cancer incidence and cancer mortality in men with cardiovascular disease.

Methods: Baseline cardiorespiratory fitness (treadmill exercise test) was assessed in 565 men aged 58.

Routine comprehensive Aspergillus screening of bronchoalveolar lavage samples in lung transplant recipients.

Background: Invasive aspergillosis is a significant cause of morbidity and mortality in lung transplant recipients (LTRs). Early diagnosis may improve outcome, yet is challenging. We assessed the diagnostic yield of a routine, comprehensive, prospectively employed Aspergillus screening strategy in LTRs.

The preventive role of cardiorespiratory fitness in current male smokers who meet the American Cancer Society criteria for lung cancer screening: a prospective pilot study.

Purpose: Survival benefits could be potentially improved by adding cardiorespiratory fitness (CRF) to lung cancer screening. The current pilot study aimed to assess the association between CRF and adverse outcomes in current male smokers who are meeting the American Cancer Society (ACS) criteria for lung cancer screening.

Methods: A total of 260 men with a baseline CRF assessment (treadmill exercise test) who are met the ACS lung cancer screening criteria ("current smokers aged 55-74 years with ≥ 30 pack/years smoking history") were prospectively studied.

Reference Standards for Ventilatory Threshold Measured With Cardiopulmonary Exercise Testing: The Fitness Registry and the Importance of Exercise: A National Database.

Background: Established reference standards for the ventilatory threshold (Vt) are lacking. The aim of this study was to develop reference standards for the Vt derived from cardiopulmonary exercise testing (CPX) using treadmill and cycle ergometry.

Methods: Seven laboratories experienced in CPX administration with established quality control procedures contributed to the Fitness Registry and the Importance of Exercise: A National Database (FRIEND) from April 2014 through February 2019.

Cardiorespiratory Fitness, Smoking Status, and Risk of Incidence and Mortality From Cancer: Findings From the Veterans Exercise Testing Study.

Background: To assess the joint and stratified associations between cardiorespiratory fitness (CRF), incidence, and mortality from cancer in never, former, and current male smokers.

Methods: CRF (treadmill exercise test) was assessed in 4694 men (never smokers [n = 1715]; former smokers [n = 1602], 32.4 [30.

Improved Survival With Higher Pre-diagnosis Cardiorespiratory Fitness in Men Who Developed Digestive System Cancers: A Prospective Pilot Study.

Background/aim: Digestive system cancers are the leading cause of cancer mortality and have poor survival particularly in men. The study aimed to assess the association between pre-diagnosis cardiorespiratory fitness (CRF) and cancer mortality in a pilot sample of men who developed digestive system cancers.

Patients And Methods: Pre-diagnosis CRF (treadmill exercise test) was assessed in 342 men (68.

Cardiorespiratory Fitness, Lung Cancer Incidence, and Cancer Mortality in Male Smokers.

Introduction: The preventive role of cardiorespiratory fitness in lung cancer among smokers is unknown. This study aims to evaluate the association between cardiorespiratory fitness and lung cancer incidence and cancer mortality in former and current male smokers.

Methods: From 1987 to 2014, cardiorespiratory fitness (quantified from treadmill exercise testing) was assessed in 2,979 men (former smokers, n=1,602; current smokers, n=1,377) aged 59.

Cardiorespiratory fitness and cancer in women: A prospective pilot study.

Purpose: To assess the association between cardiorespiratory fitness (CRF) and the incidence and mortality from cancer in women, and to evaluate the potential public health implications for cancer prevention.

Methods: Maximal exercise testing was performed in a pilot cohort of 184 women (59.3 ± 15.