Surgical Margins of Nonmelanoma Skin Cancers in Mohs Surgery: Dermoscopy Versus Naked Eye.

Background: Mohs micrographic surgery (MMS) offers high cure rates for nonmelanoma skin cancer (NMSC) but relies on precise margin assessment, traditionally initiated by the naked eye. Dermoscopy has emerged as a potential tool to improve margin delineation.

Objective: To compare the efficacy of dermoscopic versus naked eye evaluation in marking initial MMS margins for NMSC.

Hydroxychloroquine-Induced Nonthrombocytopenic Purpura: A Case Series.

Hydroxychloroquine (HCQ) is a disease-modifying anti-rheumatic medication for the treatment of various autoimmune conditions. A rare side effect of HCQ is thrombotic thrombocytopenic purpura (TTP). We present two cases of patients who developed purpura that did not meet TTP criteria following treatment with HCQ.

Biologic Treatment Options for Pediatric Psoriasis and Atopic Dermatitis-A Review.

: Severe, recalcitrant cases of pediatric psoriasis or atopic dermatitis may necessitate treatment with biological agents; however, this may be difficult due to lack of treatment options and standardized treatment guidelines. This review evaluates the biological treatment options available, including off-label uses, and provides a basic therapeutic guideline for pediatric psoriasis and atopic dermatitis. : A PubMed review of biological treatments for pediatric psoriasis and atopic dermatitis with information regarding age, efficacy, dosing, contra-indications, adverse events, and off-label treatments.

Treatment of histoid leprosy: a lack of consensus.

Histoid leprosy is a rare variant of leprosy with a unique clinical presentation and bacilli rich histology. These patients are large reservoirs for disease and vectors for spread, making prompt diagnosis and treatment crucial. To date, no consensus on treatment and duration exists.

Biologic Treatment Options for Pediatric Psoriasis and Atopic Dermatitis.

Severe, recalcitrant cases of pediatric psoriasis or atopic dermatitis may necessitate treatment with biological agents; however, this may be difficult due to lack of treatment options and standardized treatment guidelines. This review evaluates the biological treatment options available, including off-label uses, and provides a basic therapeutic guideline for pediatric psoriasis and atopic dermatitis. A PubMed review of biological treatments for pediatric psoriasis and atopic dermatitis with information regarding age, efficacy, dosing, contra-indications, adverse events, and off-label treatments.

Current biological therapies for use in HIV-positive patients with psoriasis: case report of gesulkumab used and review.

Background: Psoriasis in human immunodeficiency virus (HIV)-positive patients may be severe. Physicians may be tentative to use biologics in HIV-infected patients.

Objective: We present an HIV-positive patient with psoriasis who was treated with guselkumab.

Diabetes Mellitus Increases Risk of Hepatocellular Carcinoma in Chronic Hepatitis C Virus Patients: A Systematic Review.

Background: Rising rates of obesity, diabetes mellitus (DM), and nonalcoholic fatty liver disease (NAFLD) among chronic hepatitis C (HCV) patients may contribute to higher hepatocellular carcinoma (HCC) risk.

Aim: To perform a systematic review evaluating the impact of DM, body mass index (BMI), or steatosis on HCC risk among chronic HCV patients.

Methods: A structured keyword search of PubMed from January 1, 2001, to July 1, 2014, was performed to identify original articles evaluating the association of DM, BMI, or steatosis with HCC among adults with chronic HCV.

Cardiovascular events on board commercial maritime vessels: a two-year review.

Background: Cardiovascular diseases (CVDs) are an important concern in merchant maritime operations. They are responsible for the majority of deaths at sea that are not related to injury or violence. The objective was to better understand the epidemiology of CVD in merchant maritime operations.

[Postoperative wound healing disorders].

Aim: Investigation of the incidence of wound healing disorders in operative material and that of possible commonality with the nosocomial categories of operations and with the surgical site infections registered by the authors, respectively. OPERATIVE MATERIAL AND METHOD: The data of 33,336 operations, made in their ward, are analysed by the authors. By way of introduction the question of nomenclature is discussed which is not uniform in the literature.

[Infection register at a surgical department in Hungary].

An infection register processing 905 surgical site infections followed after 33,426 operative interventions in a 20-year period between 1977 and 1996 is described. The preliminaries of modern infection surveillance both abroad and in Hungary are outlined. The method of registration and evaluation used by the authors are also outlined in details.

[Diagnosis of intraabdominal abscesses by the ultrasound echo technique (author's transl)].

The diagnosis of abdominal abscesses with diagnostic methods generally used up to the present has not proved to be accurate and reliable. The authors give an account of their experience with a new ultrasound echo technique. By employing this technique, abdominal abscesses and effusions can be visualized with accuracy and their size can also be measured.

In situ preformed auto-alloplastic replacement in the treatment of femoropopliteal vascular obstruction.

A method of in situ preformed auto-alloplastic replacement for the treatment of long femoro-poplitela vascular obstructions is described on the basis of highly promising experimental results. A macropouous tube made of aplastic net and obturated with a silicone rubber mandril was implanted next to the obstructed vascular section. The two ends of the live auto-alloplastic tube formed in situ around the mandril were joined in a second operation to the femoral and popliteal arteries.