Management of Pelvic Pain in Patients with Crohn's Disease-Current Overview.

Crohn's disease (CD) is a subtype of chronic inflammatory bowel diseases (IBD) with characteristic skip lesions and transmural inflammation that may affect the entire gastrointestinal tract from the mouth to the anus. Persistent pain is one of the main symptoms of CD. This pain has multifactorial pathogenesis, but most often arises from intestinal inflammation itself, as well as from gut distention or partial intestinal obstruction.

Short-chain fatty acids-microbiota crosstalk in the coronavirus disease (COVID-19).

The novel coronavirus disease (COVID-19) still remains a major challenge to the health-care systems worldwide, inciting ongoing search for pharmaceutical and non-pharmaceutical interventions which could benefit patients already infected with SARS-CoV-2 or at increased risk thereof. Although SARS-CoV-2 primarily affects the respiratory system, it may also infect other organs and systems, including gastrointestinal tract, where it results in microbial dysbiosis. There is an emerging understanding of the role the gut microbiota plays in maintaining immune homeostasis, both inside the gastrointestinal tract and beyond (i.

Oxygen Binding by Co(II) Complexes with Oxime-Containing Schiff Bases in Solution.

The present work describes the complexation properties of two oxime-containing Schiff bases (used as ligands), viz. 2-hydroxyimino-N'-[1-(2-pyridyl)ethylidene]propanohydrazone (Hpop) and 2-hydroxyimino-N'-[(pyridine-2-yl)methylidene]propanohydrazone (Hpoa), with Co(II) ions in DMSO/water solution. Volumetric (oxygenation) studies were carried out to determine the uptake of molecular oxygen O in the formation of the complexes Co(II)-Hpop and Co(II)-Hpoa.

Hypervelocity cluster ion impacts on free standing graphene: Experiment, theory, and applications.

We present results from experiments and molecular dynamics (MD) simulations obtained with C and Au impacting on free-standing graphene, graphene oxide (GO), and graphene-supported molecular layers. The experiments were run on custom-built ToF reflectron mass spectrometers with C and Au-LMIS sources with acceleration potentials generating 50 keV C and 440-540 keV Au . Bombardment-detection was in the same mode as MD simulation, i.

Ejection-ionization of molecules from free standing graphene.

We present the first data on emission of C60- stimulated by single impacts of 50 keV C602+ on the self-assembled molecular layer of C deposited on free standing 2 layer graphene. The yield, Y, of C60- emitted in the transmission direction is 1.7%.

BODY SOMATIC TYPE INFLUENCE ON THE SPINAL CURVATURES IN EARLY AGE SCHOOL CHILDREN: PRELIMINARY REPORT.

Introduction: Sedentary lifestyle and its consequences are becoming a serious problem not only among the elderly but also relate to children. Reduced muscle mass, disorder of normal spinal curves or problems related to the percentage of body fat are part of physical activity limitation. The aim of this study was to assess the relationship between somatic type of the body and spinal curvatures in school children.

Single impacts of keV fullerene ions on free standing graphene: Emission of ions and electrons from confined volume.

We present the first data from individual C60 impacting one to four layer graphene at 25 and 50 keV. Negative secondary ions and electrons emitted in transmission were recorded separately from each impact. The yields for C(n)(-) clusters are above 10% for n ≤ 4, they oscillate with electron affinities and decrease exponentially with n.

Microscopic insights into the sputtering of thin organic films on Ag{111} induced by C60 and Ga bombardment.

Molecular dynamics computer simulations have been employed to model the bombardment of Ag{111} covered with three layers of C6H6 by 15 keV Ga and C60 projectiles. The study is aimed toward examining the mechanism by which molecules are desorbed from surfaces by energetic cluster ion beams and toward elucidating the differences between cluster bombardment and atom bombardment. The results show that the impact of the cluster on the benzene-covered surface leads to molecular desorption during the formation of a mesoscopic scale impact crater via a catapulting mechanism.

Enhancement of sputtering yields due to C60 versus Ga bombardment of Ag[111] as explored by molecular dynamics simulations.

The mechanism of enhanced desorption initiated by 15-keV C60 cluster ion bombardment of a Ag single crystal surface is examined using molecular dynamics computer simulations. The size of the model microcrystallite of 165,000 atoms and the sophistication of the interaction potential function yields data that should be directly comparable with experiment. The C60 model was chosen since this source is now being used in secondary ion mass spectrometry experiments in many laboratories.