Diabetes mellitus: Preventive and curative therapies with aqueous extract of Blume (Rubiaceae) in Wistar rats.

Background And Aim: African traditional healers use Blume to treat diseases such as diabetes mellitus, malaria, dysentery, constipation, and hemorrhoids. This study aimed to assess the hypoglycemic, lipid-lowering, and antioxidant properties of extract (AERS) in type 1 diabetic (T1D) and insulin-resistant (T2D) rats.

Experimental Procedure: The induction of T1D was made by intraperitoneal administration of streptozotocin (55 mg/kg b.

leaf inhibits the activity of carbohydrate digesting enzymes and improves the insulin resistance induced in rats by dexamethasone.

Background: is a plant used in traditional African medicine to treat diabetes mellitus. This study aimed to evaluate the preventive antidiabetic potential of the aqueous extract of leaves (AETD) in insulin resistant rats.

Methods: A quantitative phytochemical study of AETD was carried out to determine the contents of total phenols, tannins, flavonoids, and saponins.

Efficacy of Blume on Free Radical Scavenging, Inhibition of -Amylase and -Glucosidase Activity, and Blood Glucose Level.

(Rubiaceae) is a plant used in African medicine for the treatment of diabetes. The aim of this study was to evaluate the antioxidant, enzyme inhibitory, and hypoglycemic effects of extract (RSE). The contents of phenols, tannins, and flavonoids were determined by phytochemical screening.

Hypolipidemic and anti-atherosclerogenic effects of aqueous extract of Ipomoea batatas leaves in diet-induced hypercholesterolemic rats.

Objective: Ipomoea batatas (L.) Lam. is a food plant used in African traditional medicine to treat cardiovascular diseases and related conditions.

Hypoglycemic, antidyslipidemic and antioxydant effects of barks extract on high-fat diet and streptozotocin-induced type 2 diabetes rats.

Backgroud: is a plant belonging to the Sapotaceae family and used in traditional medicine in the treatment of diabetes mellitus. The aim of this work was to evaluate the hypoglycemic, antidyslipidemic and antioxidant effects of on type 2 diabetic rats.

Methods: To induce type 2 diabetes mellitus (T2DM), animals were fed a high-fat diet for 4 weeks followed by an intraperitoneal injection of 35 mg/kg of streptozotocin.