Publications by authors named "Bart van der Sluis"

The mechanisms allowing the widespread invasive pest to survive from early spring until the availability of the first fruit crops are still unclear. Seasonal biology and population dynamics of were investigated in order to better understand the contribution of the early spring hosts to the infestation of the first fruit crops of the season. We identified hosts available to in early spring and assessed their suitability for the pest oviposition and reproductive success under field and laboratory conditions.

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The invasive spotted wing drosophila , a fruit fly of Asian origin, is a major pest of a wide variety of berry and stone fruits in Europe. One of the characteristics of this fly is its wide host range. A better knowledge of its host range outside cultivated areas is essential to develop sustainable integrated pest management strategies.

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Pathological cardiac hypertrophy is characterized by a shift in metabolic substrate utilization from fatty acids to glucose, but the molecular events underlying the metabolic remodeling remain poorly understood. Here, we investigated the role of liver X receptors (LXRs), which are key regulators of glucose and lipid metabolism, in cardiac hypertrophic pathogenesis. Using a transgenic approach in mice, we show that overexpression of LXRα acts to protect the heart against hypertrophy, fibrosis, and dysfunction.

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