Publications by authors named "Bart Van Dooren"

Background: Evolution of the surgical approach for total hip arthroplasty (THA) has led to the development of the minimally invasive direct superior approach (DSA). It is hypothesized that the DSA reduces postoperative pain and hospital length of stay (LOS). We aimed to provide an overview of current evidence on clinical, functional, and radiological outcomes with respect to risk of revision, complications, pain scores, physical function, operative time, LOS, blood loss, radiological outcomes, and learning curve.

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Background: The use of dual mobility (DM) cups has increased quickly. It is hypothesized that femoral neck taper geometry may be involved in the risk of prosthetic impingement and DM cup revision. We aim to (1) explore the reasons for revision of DM cups or head/liners and (2) explore whether certain femoral neck characteristics are associated with a higher risk of revision of DM cups.

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Background And Purpose: The direct superior approach (DSA) is a modification of the posterolateral approach (PLA) for total hip arthroplasty (THA). Patient-reported outcome measures (PROMs) of the DSA have not been investigated previously using nationwide data. Our aim was to assess PROMs after THA using the DSA compared with the PLA and, secondarily, with the anterior approach (DAA).

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Background And Purpose: Periprosthetic femoral fracture (PPF) after total hip arthroplasty (THA) is a serious complication, as it often is followed by functional deficits and morbidity. There is no consensus regarding the optimal stem fixation method and whether additional cup replacement is beneficial. The aim of our study was to perform a direct comparison of reasons and risk of re-revision between cemented and uncemented revision THAs following PPF using registry data.

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Background And Purpose: The direct superior approach (DSA) is a modification of the classic posterolateral approach (PLA) for total hip arthroplasty (THA), in which the iliotibial band and short external rotators are spared. The revision rate of the DSA has not been investigated previously using arthroplasty registry data. We examined the reasons and risk of revision of the DSA, compared with the direct anterior approach (DAA) and PLA.

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Corneal guttae, which are the abnormal growth of extracellular matrix in the corneal endothelium, are observed in specular images as black droplets that occlude the endothelial cells. To estimate the corneal parameters (endothelial cell density [ECD], coefficient of variation [CV], and hexagonality [HEX]), we propose a new deep learning method that includes a novel attention mechanism (named fNLA), which helps to infer the cell edges in the occluded areas. The approach first derives the cell edges, then infers the well-detected cells, and finally employs a postprocessing method to fix mistakes.

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Article Synopsis
  • * A large-scale study involving nearly 4,700 keratoconus cases and over 116,000 controls identified 36 genomic regions linked to the disease, highlighting issues with collagen integrity and cell differentiation as crucial factors.
  • * The findings reveal shared genetic mechanisms with other corneal diseases and suggest that the identified genetic variants account for 12.5% of keratoconus's genetic risk, paving the way for future diagnostic tests to assess susceptibility.
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Article Synopsis
  • - The study aimed to evaluate the prevalence of eyelid disorders, meibomian gland dysfunction (MGD), and associated ocular surface diseases in patients at routine eye consultations.
  • - Data was collected from 6,525 patients across 349 ophthalmologists, revealing that 78.3% of patients had eyelid disorders, with significant links to conditions like dry eye, diabetes, and allergies.
  • - The findings indicated that eyelid disorders not only affected vision but also had notable impacts on daily activities, emotional well-being, and sleep quality, particularly for those with concurrent MGD and dry eye.
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Introduction: During our clinical practice and research, we encountered an interchangeability problem when using the SP-2000P and SP-3000P TopCon corneal specular microscopes (CSMs) (TopCon Medical Systems, Tokyo, Japan) regarding the endothelial cell count (ECC). We describe a method to improve interchangeability between these CSMs.

Methods: Five consecutive good-quality endothelial cell photographs were obtained in 22 eyes of 11 subjects.

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Purpose: To evaluate the incidence of Acanthamoeba keratitis in the Netherlands between 2009 and 2015 and to analyse predicting factors for treatment outcome.

Methods: Patient characteristics, diagnostic methods, diagnostic delay, therapy prior to and after diagnosis, and visual outcome were obtained from medical files of all patients diagnosed with Acanthamoeba keratitis in the Netherlands between 2009 and 2015. A logistic regression analysis on treatment failure, defined as a best corrected visual acuity of less than 20/40 Snellen decimals (i.

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Purpose: To describe the results of cataract extraction with toric intraocular lens (IOL) implantation in patients with preexisting astigmatism from three corneal conditions (keratoconus, postkeratoplasty, and postpterygium surgery).

Methods: Cataract patients with topographically stable, fairly regular (although sometimes very high) corneal astigmatism underwent phacoemulsification with implantation of a toric IOL (Zeiss AT TORBI 709, Alcon Acrysof IQ toric SN6AT, AMO Tecnis ZCT). Postoperative astigmatism and refractive outcomes, as well as visual acuities, vector reduction, and complications were recorded for all eyes.

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Purpose: To report endothelial cell density (ECD) after posterior lamellar keratoplasty (PLK).

Design: Prospective, interventional case series.

Methods: In a single institution, PLK was performed in 15 eyes of 15 patients with pseudophakic bullous keratopathy (PPBK), Fuchs endothelial dystrophy (FED), or both.

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Purpose: To report on the calibration of the Topcon SP-2000P specular microscope and the Endothelial Cell Analysis Module of the IMAGEnet 2000 software, and to establish the validity of the different endothelial cell density (ECD) assessment methods available in these instruments.

Methods: Using an external microgrid, we calibrated the magnification of the SP-2000P and the IMAGEnet software. In both eyes of 36 volunteers, we validated 4 ECD assessment methods by comparing these methods to the gold standard manual ECD, manual counting of cells on a video print.

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Purpose: To report the midterm endothelial cell density measurements after posterior lamellar keratoplasty (Melles techniques).

Design: Cohort study.

Methods: Fifteen consecutive eyes of 15 patients in whom a posterior lamellar keratoplasty procedure was performed for pseudophakic bullous keratopathy or Fuchs' endothelial dystrophy were evaluated.

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Objective: To quantify the toxicity of trypan blue on human corneal cells according to exposure time and concentration.

Methods: Three in vitro experiments were performed. (1) We exposed cultured human corneal fibroblasts to trypan blue (0.

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Purpose: To measure the recipient endothelial cell loss after the Melles technique for deep anterior lamellar keratoplasty.

Methods: In 21 eyes of 21 patients, a deep anterior lamellar keratoplasty procedure was performed. Before surgery and at 6, 12, and 24 months after surgery, specular microscopy was performed to evaluate the endothelial cell density.

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