Pentoxifylline attenuates HPV-16 associated necrosis in placental trophoblasts.

Purpose: Human papillomaviruses (HPV) have been associated with placental inflammation resulting in high-risk preterm birth. The premise for this study was that treatment with anti-inflammatory pentoxifylline would inhibit HPV-mediated placental cell death. The objectives were: (1) to study the effects of HPV-16 exposure on trophoblast cells and (2) to evaluate pentoxifylline in preventing the damaging effects of HPV-16.

A concise method of calculating fetal weight percentile.

Objective: Assessment of fetal growth used in clinical decision making for managing pregnancies is based on percentiles relative to normal values for gestational age. Most clinicians utilize visual interpolation of look-up tables or graphs, which is neither accurate nor convenient. Calculation of growth percentile by numerical integration formulas requires digital computers with advanced computational capabilities and/or the storage of large data tables.

Recurrence of microangiopathic hemolytic anemia after apparent recovery from the HELLP syndrome. A case report.

Background: The syndrome of hemolytic anemia, elevated liver enzymes and low platelets (HELLP) can accompany preeclampsia and eclampsia. Delivery of the infant usually results in improvement in the mother's condition, with the recovery time dependent on the severity of the disease. We report a case of eclampsia with the HELLP syndrome in which microangiopathic hemolytic anemia (MAHA) and thrombocytopenia recurred after apparent recovery.