kills in a polyphosphate-dependent manner.

Due to their frequent coexistence in many polymicrobial infections, including in patients with cystic fibrosis or burn/chronic wounds, many studies have investigated the mechanistic details of the interaction between the opportunistic pathogens and rapidly outcompetes under cocultivation conditions which is mediated by several of 's virulence factors. Here, we report that polyphosphate (polyP), an efficient stress defense system and virulence factor in , plays a role in the pathogen's ability to inhibit and kill in a contact-independent manner. We show that cells characterized by low polyP levels are less detrimental to growth and survival while the Gram-positive pathogen is significantly more compromised by the presence of cells that produce high levels of polyP.

kills in a polyphosphate-dependent manner.

Due to their frequent coexistence in many polymicrobial infections, including in patients with burn or chronic wounds or cystic fibrosis, recent studies have started to investigate the mechanistic details of the interaction between the opportunistic pathogens and . rapidly outcompetes under co-cultivation conditions, which is mediated by several of 's virulence factors. Here, we report that polyphosphate (polyP), an efficient stress defense system and virulence factor in , plays a role for the pathogen's ability to inhibit and kill in a contact-independent manner.