Transformation/dissolution examination of antimony and antimony compounds with speciation of the transformation/dissolution solutions.

Speciation is held to be a key factor in controlling the ecotoxicity of metals in solution. Using the United Nations transformation/dissolution protocol (T/DP) for metals and sparingly soluble metal compounds, we have examined the transformation/dissolution (T/D) characteristics in terms of the concentrations of total dissolved Sb at pH 6 and 8.5 in 1, 10, and 100 mg/L loadings over 7 d as well as the concentrations of Sb(III) and Sb(V) at the 1 mg/L loadings over 28 d, of sodium hexahydroxoantimonate (NaSb(OH)(6)), antimony metal (Sb), antimony trioxide (Sb(2) O(3)), antimony sulfide (Sb(2) S(3)), sodium antimonate (NaSbO(3)), antimony tris(ethylene glycolate) (Sb(2) (C(2) H(4) O(2) )(3)), antimony trichloride (SbCl(3)), antimony triacetate (Sb(CH(3) COO)(3)), and antimony pentoxide (Sb(2) O(5) ).

Bilateral effects of unilateral intrastriatal GDNF on locomotor-excited and nonlocomotor-related striatal neurons in aged F344 rats.

In order to determine its effects on locomotor-related striatal electrophysiology in aged rats, glial cell line-derived neurotrophic factor (GDNF) was infused (vehicle or 30mug) into the right striatum of 24-25-month-old Fischer 344 (F344) rats. Multi-wire electrode arrays were then chronically implanted in striatum bilaterally. Thirty days later, striatal electrophysiological activity was recorded during freely moving conditions.