Low power supercycled TPPM decoupling.

Improving the spectral sensitivity and resolution of biological solids is one of the long-standing problems in nuclear magnetic resonance (NMR) spectroscopy. In this report, we introduce low-power supercycled variants of two-pulse phase-modulated (TPPM) sequence for heteronuclear decoupling. The utility of the sequence is shown by improvements in the transverse relaxation time of observed nuclei (with H decoupling) with its application to different samples (uniformly C, N, H-labeled GB1 back-exchanged with 25% HO and 75% DO, uniformly C, N, H-labeled human derived Asyn fibril back-exchanged with 100% HO and uniformly C, N -labeled human derived Asyn fibril) at fast MAS using low radiofrequency (RF) fields.

ImageJ2: ImageJ for the next generation of scientific image data.

Background: ImageJ is an image analysis program extensively used in the biological sciences and beyond. Due to its ease of use, recordable macro language, and extensible plug-in architecture, ImageJ enjoys contributions from non-programmers, amateur programmers, and professional developers alike. Enabling such a diversity of contributors has resulted in a large community that spans the biological and physical sciences.