Effects of propolis on lingual mucosa response of hamsters submitted to experimental carcinogenesis.

Objective: To assess the tissue reaction of the lingual mucosa in hamsters submitted to daily, alternating, topical applications of 9,10-dimethyl-1,2-benzanthracene (DMBA) and a commercial brand of an ethanol propolis extract (EPE).

Methods: A total of 60 hamsters were divided into three groups with two experimental periods (13 and 20 weeks). The lateral edge of the tongue was submitted to daily, alternating, topical applications of 0.

Effect of propolis on mast cells in wound healing.

Wound healing is divided into three phases: inflammatory, proliferative and remodeling. Mast cells participate in all these phases. The aim of the present study was to determine the effects of propolis on the population of mast cells in oral surgical wounds in comparison to the results obtained with dexamethasone.