[Extemporaneous histologic examination of cutaneous carcinoma of the face].

One hundred thirty-eight skin cancers of the face were reviewed retrospectively in order to evaluate the extemporaneous histology examination. The results obtained were satisfactory and in agreement with those in the literature. This technique is perfectly adapted to cancers with a facial localization.

[The use of toluidine blue in the diagnosis of neoplastic lesions of the oral cavity].

Toluidine blue staining is not used extensively in the diagnosis of mucosal lesions of the buccal cavity. It is, however, an effective aid, being a diagnostic tool of choice, particularly during screening for neoplastic lesions in populations at risk.

[The use of cryotherapy in oral pathology. Our experience in 36 cases].

Cryotherapy is a simple to use, weakly invasive technique provoking only moderate complications in the treatment of certain mucosal lesions of the buccal cavity. Indications of choice for this type of treatment are angioma and papilloma. Long term follow up of patients treated for reactive keratosis or epithelioma in situ is at present insufficient to establish precise indications.

[The value of extemporaneous study of the surgical margins of cancers of the upper aero-digestive tract. Apropos of 129 cases of oral and oropharyngeal tumors].

129 patients, who had oral cavity or oropharyngeal carcinoma underwent excision with intraoperative histopathologic examination. Thanks to this method, the number of satisfying resections has increased from 25% to 75%. Whatever the quality of the surgical excision may be, postoperative radiotherapy improves the prognosis.

[Medical treatment of osteoradionecrosis].

The medical treatment of radiation-induced osteitis is advocated by all, with highly variable practical modalities. In our historical series, we have noted 12 good results out of 48 patients treated. In the light of R.

[Basocellular epitheliomas of the eyelids].

On the basis of a retrospective study of 354 basal-cell epitheliomas of the eyelids, we present a study of the most frequently used treatments: surgery, conventional radiation therapy and curietherapy. The results of treatment, both functional and oncological, are generally satisfactory, whatever the method chosen, but with a set of arguments in favor of surgery. The major therapeutic indications are discussed, without formally ruling out any treatment.

[Epidermoid carcinoma of the lip. The contribution of surgery. Apropos of 429 cases].

The surgical treatment of epidermoid carcinoma of the lip too rarely resorts to pluri-disciplinary confrontation, although all the possible techniques, i.e. surgery, curietherapy and radiation therapy, are effective.

Analysis of the results of the micronucleus test in patients presenting upper digestive tract cancers and in non-cancerous subjects.

A micronucleus test was performed on 75 subjects of whom 38 presented with cancer of the upper digestive tract and 37 were free of disease; the absence of cancerous or pre-cancerous lesions in this latter group was confirmed by endoscopy and vital staining. The daily levels of alcohol and tobacco consumption of the 75 subjects were determined by precise questioning: 78% of the non-cancerous subjects smoked less than 10 g of tobacco per day whereas 79% of the cancer patients smoked 10 g or more daily. The alcohol intake of 78% of the non-cancerous subjects and 63% of the cancer patients was less than 101 ml per day.

[Cancer registry of Calvados, hospital registry of the François- Baclesse Center and mortality statistics: comparisons].

Incidence rates of the cancer registry of the department of Calvados were compared, by site and by age group, with those obtained from the cancer registry of the comprehensive cancer center in Caen, concerning the population of the department of Calvados. In males, these rates are approximately similar for head and neck sites; for the hospital registry they are 50% of those recorded by the population registry for lung cancer, and 30% for prostatic cancer. In females, the all-sites rates are nearly identical for the youngest age groups and 50% for the older.

[Lymphatic invasion of cancers of the oral cavity. A diagnostic strategy].

The diagnostic of ganglionnary invasion in oral cancer is established throughout the histological investigation practiced during the operation. This histological inquiry has to be rigorous and logical, in conformity with the anatomical particularities of the drainage tubes of the oral mucous. The accurate execution of this diagnostical strategy applied to the ganglionnary invasion improves the prognostic but requires a good logistic support.

[Screening for cancer of the upper aerodigestive tract in a high-risk population].

From the data collected in the Cancer Registry of Calvados, a screening program for neoplastic lesions of the whole upper digestive and respiratory tract was performed in a canton where esophageal cancer incidence is very high. 137 men underwent this examination for mouth, pharyngo-larynx and esophagus. None neoplastic lesion was revealed but histologic and cytologic swabs showed some abnormalities that are now being studied.

[Detection of buccal cavity cancers with toluidine blue (author's transl)].

When malignant tumours of the oral cavity are of a small size, they are asymptomatic during a long time, and it is difficult to detect them. A method permitting to discover them more easily during the examination would be a precious rescue. In this aim, we have tested the oral coloration with toluidine-blue in 50 patients with a high risk of malignant tumour.

[Functional rehabilitation of irradiated maxillary bones (author's transl)].

The teeth should be conserved before radiotherapy: --in patients with good buccodental hygiene the teeth are conserved and fluoride treatment instituted,--when hygiene is only moderate, the mandibular teeth outside of the treated area are left in place and fluoride treatment is also attempted. The crowns are conserved, and an attempt is even made in some cases to apply them, as for example on the canines.--when hygiene is inexistant, all the teeth are extracted.

[Micrographic aspect of mandibular osteoradionecrosis (author's transl)].

Fragments of the lower jaw from 42 patients with carcinoma of the oral cavity or oropharynx, and treated primarely with fraction radiotherapy, were excised for radiation osteonecrosis 6 month to 10 years after irradiations. The excised specimens are X-rayed before being coated with methylmetacrylate. They are then cut into thick sections along lines detailled on the X-ray films.

[Arterial embolization in malignant neoformations of the face and neck].

On the basis of 25 cases of embolisation for cervico-facial tumours, it was possible to demonstrate the value of this technique in the treatment of local haemorrhage and in the relief of pain in patients with a lesion beyond hope of any treatment.

[Non-surgical treatment of tuberous angiomas of the lip. Apropos of 26 cases].

Among the various methods that can be used for the treatment of hemangiomas of the face, the use of Yttrium 90 radium needles seems to give the most satisfactory esthetic results. One application is usually sufficient to obtain disappearance of the tumor. Spontaneous regression is now a generally accepted fact, however, and the essential problem remains whether hamangiomas should be treated all when no complications are present.