CONSTRICTING ESOPHAGEAL LESIONS. COLON INTERPOSITION FOR REPLACEMENT, COMBINED WITH RADIOTHERAPY FOR CARCINOMA.

The use of colon for esophageal replacement is a procedure that should be considered in the treatment of benign and malignant esophageal lesions. The five-year survival data following operations for carcinoma of the esophagus are not outstanding. The combination of colon transplantation and radiotherapy before and after operation is a procedure that should be utilized if an effort is to be made to increase the survival rate.

Anal carcinoma.

Carcinoma of the anus is a rare tumor when skin tumors which may have arisen from the perianal skin are excluded. A significant proportion of anal carcinomas, exclusive of those from perianal skin, may very well have their origin from the intermediate zone of transitional epithelium and its and ducts, which would account for the different histological patterns presented by these cancers. These tumors are frequently described as of low grade malignancy and indeed some of them may be; but, the majority behave as very aggressive carcinomas, capable not only of rapid and extensive local invasion but also capable of lymph node metastasis.

The effect of vagotomy and pyloroplasty on the maximal acid response to histamine.

Pyloroplasty alone does not significantly alter the maximal acid response to histamine but it is considerably reduced in those patients who have had a vagotomy.