SNHG5 enhances Paclitaxel sensitivity of ovarian cancer cells through sponging miR-23a.

Background: Ovarian cancer is one of the most lethal gynecological malignancies throughout the world. Long non-coding RNA (lncRNA) small nucleolar RNA host gene 5 (SNHG5) has been reported to play an important role in several human cancers, but the role of SNHG5 in the chemoresistance of ovarian cancer cells is yet elusive.

Method: The expression of SNHG5 and miR-23a were determined by quantitative reverse transcriptase polymerase chain reaction.