A nine-year review of 841 children tested by transtympanic electrocochleography.

The case notes of 841 subjects who had had ECochG carried out between January 1972 and December 1980, were examined and the results compared with PTA results in 263 cases in which these were available. ECochG was found to be a good predictor of peripheral hearing as long as its limitations were recognized, and some of these are discussed. BSER, which has similar limitations, was also found to be a good predictor of peripheral hearing, although slightly less sensitive, and sometimes gave additional information on the hearing loss and the clinical state of the patient.

[Comparative study of the effects of probucol, fenofibrate and clofibrate on liver ultrastructure in rats (author's transl)].

The effects on rat liver of probucol (250 or 500 mg/kg/24 h), clofibrate (250 mg/kg/24 h) and fenofibrate (100 mg/kg/24 h) were compared after 28 days' treatment. Th bodyweight of animals treated with probucol 250 mg/kg/24 h has increased, as compared with a control group of untreated animals. The increase in liver weight and live weight/bodyweight ratio was greater in rats treated with clofibrate or fenofibrate than in rats treated with probucol.

Comparative ultrastructural study of rat hepatocytes after treatment with the hypolipidemic agents probucol, clofibrate, and fenofibrate.

Experimental findings are reported for two similarly conducted studies. One was designed to compared rat liver cell ultrastructure during and after 91 d of dosing with probucol, a hypocholesterolemic agent, and clofibrate, a hypolipidemic drug known to elicit marked alteration of rat hepatocellular morphology. The second was designed to similarly assess male rats after 28 d of treatment with the hypolipidemic agent fenofibrate.

Eight-year toxicity study in monkeys and reproduction studies in rats and rabbits treated with probucol.

Probucol [4,4'-(isopropylidenedithio)bis(2,6-di-tert-butylphenol)], a hypocholesterolemic agent, was given orally to male and female rhesus monkeys at 0, 60, 125, 250, and 500 mg/kg . d for more than 8 yr without adverse effect. Of 40 monkeys on test, 14 were killed for interim studies (wk 81 and 102), 21 were maintained for more than 8 yr, and 5 were submitted for necropsy for conditions unrelated to treatment.

Disparity analysis of images.

An algorithm for matching images of real world scenes is presented. The matching is a specification of the geometrical disparity between the images and may be used to partially reconstruct the three-dimensional structure of the scene. Sets of candidate matching points are selected independently in each image.

Handling Perishable Foods.

Food service industry management has been interested in help to meet sanitary regulations, reduce food spoilage, lengthen keeping quality, and prevent foodborne illness. Materials were developed for 1-day workshops to provide practical suggestions for handling perishable and preserved foods. Products included were meats, poultry and eggs, milk and dairy products, delicatessen, fruits, vegetables and seafood.

Freezing Points and Milk Adulteration.

The freezing point study of raw and retail milk samples as reported in the Journal of Milk and Food Technology (July, 1976) has continued for retail samples. The Pennsylvania Department of Agriculture adopted a regulation which considers milk with a freezing point of above -0.525 C to be adulterated.

An experimental study on the onset of endolymphatic secretion in chick embryos.

Extirpation of the endolymphatic anlage of the ear vesicle or that part of the ear placode which develops into the endolymphatic anlage in chick embryos, resulted in the absence of the endolymphatic system. In specimens of which the endolymphatic anlage was removed on the fourth day, healing of the wound was completed soon after the fifth day of incubation. Most of these experimental animals developed endolymphatic hydrops at a later stage.