Publications by authors named "Barnaby Roberts"

Article Synopsis
  • Some countries are changing their rules about blood donation because they believe the risk of a disease called variant Creutzfeldt-Jakob disease (vCJD) has decreased since it was a big concern in the past, especially in the UK.
  • Experts held a meeting to talk about how to learn more about the disease and how to keep people safe during blood transfusions.
  • They agreed that the risk of getting vCJD from blood donors who traveled or received blood in the UK is very low now, and it's important for experts in Europe to work together to create safer guidelines for blood donation.
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Plasma-derived medicinal products (PDMPs) are life-saving and life-improving therapies, but the raw material is in short supply: Europe depends on importation from countries including the United States. Plasma from donors resident in the United Kingdom has not been fractionated since 1999 when a precautionary measure was introduced in response to the outbreak of variant Creutzfeldt-Jakob disease (vCJD). Cases of vCJD have been far fewer than originally predicted in the 1990s.

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Background And Objectives: The limited supply and increasing demand of group O RhD-negative red blood cells (RBCs) have resulted in other transfusion strategies being explored by blood services that carry potential risks but may still provide an overall benefit to patients. Our aim was to analyse the potential economic benefits of prehospital transfusion (PHT) against no PHT.

Materials And Methods: The impact of three PHT strategies (RhD-negative RBC, RhD-positive RBC and no transfusion) on quality-adjusted-life-years (QALYs) of all United Kingdom trauma patients in a given year and the subset of patients considered most at risk (RhD-negative females <50 years old), was modelled.

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