Association Between Quality of Life and Drug Adherence Among Patients With Diabetes in India.

Introduction: Diabetes represents a significant global health concern. Effective diabetes management necessitates substantial behavioral and psychological modifications, including regular glucose monitoring, dietary adjustments, and medication adherence. However, treatment adherence remains suboptimal, particularly in developing countries, leading to poor glycaemic control, increased healthcare costs, and diminished quality of life (QoL).

Evidence of the Immunomodulatory Effects of Selective Serotonin Reuptake Inhibitors in Patients With Depression Through a Systematic Review.

Depression is a common illness, affecting >264 million people worldwide. According to the literature, depression patients have baseline subclinical inflammation. The immunomodulatory effects of antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), are largely unclear and poorly understood.

Challenges in the Teaching-Learning Process of the Newly Implemented Module on Bioethics in the Undergraduate Medical Curriculum in India.

The National Medical Commission of India introduced the Competency Based Curriculum in Medical Education for undergraduate medical students in 2019 with a new module named Attitude, Ethics and Communication (AETCOM) across the country. There was a consensus for teaching medical ethics in an integrated way, suggesting dedicated hours in each phase of undergraduate training. The AETCOM module was prepared and circulated as a guide to acquire necessary competency in attitudinal, ethical and communication domains.

Impact of Antibiotic Stewardship Program on Prescribing Pattern of Antimicrobials in Patients of Medical Intensive Care Unit.

Introduction: Rising concerns about antimicrobial resistance and inadequate development of effective new anti-infective drugs have stimulated universal efforts to strengthen infection-control interventions. Antimicrobial stewardship is a rational, systematic approach to promote the optimal selection, dosing, and duration of therapy for antimicrobial agents throughout the course of their use in order to improve the outcomes.

Aim: Since in Shree Krishna Hospital (SKH), Antibiotic Stewardship Program (ASP) was first implemented in 2013, this study was planned to assess any change in antimicrobial use before and after implementation of ASP and to study the rate and pattern of antimicrobial use in medical ICU.

Effect of Single Dose Betamethasone Administration in Pregnancy on Maternal and Newborn Parameters.

Introduction: Antenatal corticosteroids play an important role in preventing Respiratory Distress Syndrome (RDS) but benefits related to time between corticosteroid administration and delivery need to be explored.

Aim: To observe the effect of betamethasone administration in pregnant women at risk of preterm delivery and on foetal parameters, in terms of development of RDS.

Materials And Methods: It was a prospective observational study on pregnant women at risk of preterm delivery who were administered a single dose 24 mg injection betamethasone.

Utilization of Medicines Available at Home by General Population of Rural and Urban Set Up of Western India.

Introduction: In India, medicines are procured with prescription or without prescription by patients, which are kept at home and often are utilized in inappropriate manner. It may remain unused, get expired or may be repeated in the way of self medication. So there remains an increase chance of self-medication compared to prescribed drugs.

Personal experience narratives by students: a teaching-learning tool in bioethics.

The principles of bioethics have been identified as important requirements for training basic medical doctors. Till now, various modalities have been used for teaching bioethics, such as lectures, followed by a small case-based discussion, case vignettes or debates among students. For effective teaching-learning of bioethics, it is necessary to integrate theory and practice rather than merely teach theoretical constructs without helping the students translate those constructs into practice.

Assessment of Rationality of Fixed Dose Combinations Approved in CDSCO List.

Introduction: Fixed Dose Combination (FDC) is highly popular in the Indian pharmaceutical market and has been particularly flourishing in the last few years. Though rationality status is not clear, the pharmaceutical industry has been manufacturing and marketing FDCs.

Aim: To assess rationality of FDCs enlisted in CDSCO list and marketing in India according to pharmacokinetic (FD) and pharmacodynamic (FD) reasoning and WHO rationality criteria.

Adherence To JNC-VII and WHO-ISH guidelines of antihypertensive medications prescribed to hypertensive patients with co-morbid conditions.

The present study aims at comparing the prescribing pattern of antihypertensive drugs in essential hypertension with specific co-morbid conditions with JNC-VII and WHO-ISH guidelines. Adult patients of both sex, who were attending medicine OPD of Shri Krishna Hospital, Karamsad, Gujarat since last 6 months and being prescribed antihypertensive drug/s for hypertension, were selected for the study. Hypertensive patients with co-morbities diabetes mellitus, ischemic heart diseases, congestive heart failure, and chronic renal diseases were included in the study.

Potential Drug - Drug Interactions among Medications Prescribed to Hypertensive Patients.

Context: Drug-drug interactions(DDIs) are significant but avoidable causes of iatrogenic morbidity and hospital admission.

Aim: To detect potential drug-drug interactions among medications received by hypertensive patients.

Materials And Methods: Patients of both sex and all adult age groups, who were attending medicine out -patient department (OPD) of a tertiary care teaching rural hospital since last six months and were being prescribed antihypertensive drug/s for essential hypertension, were selected for the study.

Appropriateness of drug dose and frequency in patients with renal dysfunction in a tertiary care hospital: A cross-sectional study.

Aim: Study was aimed to assess the accuracy of drug dose and its frequency in patients with renal dysfunction in a tertiary care hospital.

Materials And Methods: This was a retrospective observational study. Patients > 18 years old, with the serum creatinine (SCr) level > 1.

Study of plasma level of atorvastatin and its effect on lipid profile.

Atorvastatin, being one of the most commonly used antihyperlipidemic agents, is prescribed frequently by physicians all over the world but only a few data is available stating its effect in different ethnic population, more so from this part of India. The present study was designed focusing mainly on local population and was planned to determine plasma level of atorvastatin 10 mg and its effect on lipid profile in newly diagnosed hyperlipidemic patients attending Medical OPD of Shri Krishna Hospital, Karamsad (Gujarat). Study-I was carried out in 6 healthy volunteers to determine t(max) after single dose of atorvastatin 10 mg under fasting conditions, on the basis of which Study-II was conducted in 15 patients, collecting blood samples at a particular time (i.