[Mechanism of development and diagnosis of aspiration pneumonia in patients with risk factors].

Aim: To optimize diagnosis of purulent lung destruction of aspiration genesis in patients with risk factors basing on algorithms.

Material And Methods: A total of 235 patients with destructive aspiration pneumonia (AP) aged 32-70 years (207 males and 28 females) were examined (fibrobronchoscopy, esophagogastroscopy, 24-h pH-metry). Statistic processing was made with nonparametric methods (ANOVA/MANOVA).

[Geoinformation technologies in phthisiology].

Special geoinformation technologies (GIS), a new method for the pictorial data presentation as space-time ratios, have emerged in the past decade. The paper considers the theory of geoinformation analysis and the possibilities of applying GIS for tuberculosis monitoring. GIS may be effectively used in phthisiology only provided that the routine procedures for tuberculosis detection are practiced widely.

[Differential diagnosis of protracted purulent destruction-complicated pneumonia in patients with risk factors].

There is some doubt upon the correct diagnosis in a third (136 (31.5%)/431) of patients (114 males and 22 females) admitted as having a diagnosis of protracted pneumonia. An algorithm of examination of patients with risk factors was developed for the differential diagnosis of different types of protracted pneumonia, including its destructive forms.

[Diagnosis of aspiration pneumonia complicated by acute purulent destruction in persons having risk factors].

Objective: To analyze the causes of development of aspiration pneumonia (AP) complicated by acute purulent pulmonary destruction (APPD) and to optimize approaches to its diagnosis, by examining the clinical picture and features of its development in patients having risk factors.

Subjects And Methods: 431 patients with purulent pulmonary diseases, including 314 (72.8%) patients with abscessed pneumonia and 117 (27.

[The treatment of preasthma patients by inhalations of calcitrin].

Calcitrin inhalations were used in the treatment of 42 patients with preasthma (chronic obstructive bronchitis--37, asthmatic bronchitis--15). The antiinflammatory and chronic obstructive bronchitis. The broncholytic effect prevailed in patients with asthmatic bronchitis.

[Various indicators of early diagnosis of the protracted course of acute pneumonia].

Humoral immunity, body reactivity, reparative function of connective tissue were investigated in 45 patients with poor-symptom acute pneumonia and in 29 lingering pneumonia cases. The patients were examined for the content of IgM, IgG and IgA, haptoglobin, seromucoid, collagen metabolism (by oxyproline) on treatment days 1-5 and 15-25. With prolongation of the inflammation resolution and transformation of the disease into a lingering form, there appeared an imbalance of immunoglobulins manifested by low values of IgG and IgA.

[Effect of calcitrin inhalation on the course of cortico-dependent bronchial asthma].

Thirty-five patients with cortico-dependent bronchial asthma were treated with calcitrin inhalations during disease exacerbation. Calcitrin was administered daily for 10-12 days in the doses increased from 1 to 3-4 Units followed by reduction to the initial dose in the presence of routine therapy. According to the clinico-laboratory, spirographic and tachographic studies, the symptoms of asthma exacerbation rapidly degressed, while asphyxia attacks ceased or were relieved.

[Suppurative-destructive complications of acute pneumonia and the principles of their treatment].

Peculiarities in the development and course of purulent complications in patients with acute pneumonia require a differentiated approach to therapy. The control of clinicoroentgenological stages of the abscess formation of pneumonia taking account of the peculiarities of a purulent process in each patient permits one to resort to differentiated therapy and to plan therapeutic measures until a complete cure of a patient. Effective treatment of a patient with lung suppuration is based on the suppression of purulent infection by massive antibiotics therapy combined with measures aimed at enhancing the defence activity of the body.

[Immunological indices and the acid phosphatase activity of the blood serum in patients with suppurative and destructive complications of acute pneumonia during the treatment/process].

The content of T and B lymphocytes, IgA, IgM and IgG as well as blood serum acid phosphatase (AP) activity were examined in 55 patients with purulent destructive complications of acute pneumonia. The patients were distributed into 2 groups depending on the disease gravity. The patients with a grave disease showed the depression of T and B immunity systems, marked deficiency of serum IgA, IgM and IgG.

[Pharmacological correction of immunologic components in the combined treatment of chronic obstructive bronchitis].

The authors provide comparative data derived during study of the time-course of changes in IgM, IgG and IgA and cellular eosinophilic and basophilic allergic reactions during application of pentoxyl and becotide alone and combined in multiple modality treatment of 161 patients with chronic obstructive bronchitis. Application of pentoxyl was accompanied mainly by quantitative increment of immunoglobulins, particularly IgA and IgG, and moderately pronounced desensitization effect that manifested by attenuation of the eosinophilic reaction and spontaneous degranulation of basophils. Application of becotide in multiple modality treatment led primarily to attenuation of the cellular allergic reactions under study and less marked increment of immunoglobulins.

[Combination of the Valsalva's maneuver with rheography for the evaluation of contactility of the right section of the heart in lung diseases].

The authors modified the Valsalva test by employing a strictly staged dosed loading with the help of a water manometer for recording rheopneumogrammes in normal individuals and in pulmonary patients. In the absence of clinical signs of cardiac pathology this method permitted to reveal latent disorders in the contractility of the right heart and its reserve capacity. The shifts in the rheographic data of the patients differed significantly from those obtained in the normals.