InsightSleepNet: the interpretable and uncertainty-aware deep learning network for sleep staging using continuous Photoplethysmography.

Background: This study was conducted to address the existing drawbacks of inconvenience and high costs associated with sleep monitoring. In this research, we performed sleep staging using continuous photoplethysmography (PPG) signals for sleep monitoring with wearable devices. Furthermore, our aim was to develop a more efficient sleep monitoring method by considering both the interpretability and uncertainty of the model's prediction results, with the goal of providing support to medical professionals in their decision-making process.

Ultrasound-guided subclavian vein catheterisation with a needle guide (ELUSIVE): protocol for a randomised controlled study.

Introduction: Central venous catheters are indispensable in modern healthcare. Unfortunately, they are accompanied by minor as well as major complications, leading to increased morbidity, mortality and costs. Immediate insertion-related complications (mechanical complications) have decreased due to the implementation of real-time ultrasound guidance, but they still occur and additional efforts to enhance patient safety are warranted.

SelANet: decision-assisting selective sleep apnea detection based on confidence score.

Background: One of the most common sleep disorders is sleep apnea syndrome. To diagnose sleep apnea syndrome, polysomnography is typically used, but it has limitations in terms of labor, cost, and time. Therefore, studies have been conducted to develop automated detection algorithms using limited biological signals that can be more easily diagnosed.

Albumin infusion rate and plasma volume expansion: a randomized clinical trial in postoperative patients after major surgery.

Background: Optimal infusion rate of colloids in patients with suspected hypovolemia is unknown, and the primary objective of the present study was to test if plasma volume expansion by 5% albumin is greater if fluid is administered slowly rather than rapidly.

Methods: Patients with signs of hypoperfusion after major abdominal surgery were randomized to intravenous infusion of 5% albumin at a dose of 10 ml/kg (ideal body weight) either rapidly (30 min) or slowly (180 min). Plasma volume was measured using radiolabeled albumin at baseline, at 30 min, and at 180 min after the start of infusion.

The importance of albumin infusion rate for plasma volume expansion following major abdominal surgery - AIR: study protocol for a randomised controlled trial.

Background: Administration of fluids to restore normovolaemia is one of the most common therapeutic interventions performed peri-operatively and in the critically ill, but no study has evaluated the importance of infusion rate for the plasma volume-expanding effect of a resuscitation fluid. The present study is designed to test the hypothesis that a slow infusion of resuscitation fluid results in better plasma volume expansion than a rapid infusion.

Methods/design: The study is a single-centre, assessor-blinded, parallel-group, randomised prospective study.

The effect of vitamin C on plasma volume in the early stage of sepsis in the rat.

Background: Previous experimental studies have shown that vitamin C has several beneficial effects in sepsis and burns, such as decreased tissue oedema, improved endothelial barrier function and decreased transcapillary leakage of plasma markers. It has still not been investigated, though, if vitamin C has any impact specifically on plasma volume. The present study aims at testing the hypothesis that vitamin C decreases plasma volume loss in sepsis.

Infusion rate and plasma volume expansion of dextran and albumin in the septic guinea pig.

Background: Intravenous fluid treatment of hypovolaemia in states of increased capillary permeability, e.g. sepsis, is often accompanied by adverse oedema formation.

Plasma volume expansion by 0.9% NaCl during sepsis/systemic inflammatory response syndrome, after hemorrhage, and during a normal state.

Objective: The objective of this study was to determine the degree of plasma volume expansion by 0.9% NaCl in relation to the infused volume, in sepsis/systemic inflammatory response syndrome (SIRS), after a standardized hemorrhage, and in a normal condition.

Design: Prospective, randomized animal study.

Importance of the infusion rate for the plasma expanding effect of 5% albumin, 6% HES 130/0.4, 4% gelatin, and 0.9% NaCl in the septic rat.

Objectives: To compare the plasma volume (PV) expanding effect of a fast infusion rate with that of a slow infusion rate of a fixed volume of 5% albumin, of the synthetic colloids, 6% hydroxyethyl starch 130/0.4 and 4% gelatin, and of 0.9% NaCl in a rat sepsis model and to compare the plasma-expanding effect among these fluids.

[Equipment and possibilities of dynamic monitoring of arrhythmia during permanent electrocardiostimulation].

The APKA cardiocomplex was developed, which diagnoses short intermittent arrhythmias in patients with and without cardiocomplexes. The cardiocomplex may operate in inpatient conditions of the cardiosurgical and cardiological units which are engaged in cardiac rhythms and in outpatient conditions of the outpatient monitoring and functional diagnosis rooms.