Anticancer activity of Turkish marine extracts: a purple sponge extract induces apoptosis with multitarget kinase inhibition activity.

Marine natural products have drawn a great deal of attention as a vital source of new drugs for the last five decades. However, marine organisms in the seas surrounding Turkey (the Black Sea, the Aegean Sea and the Mediterranean Sea) haven't been yet extensively explored. In the present study, three marine organisms (Dysidea avara, Microcosmus sabatieri and Echinaster sepositus) were sampled from the Dardanelles (Turkish Straits System, Western Turkey) by scientific divers, transferred to the laboratory and then were extracted with 70% ethanol.

Human exposure to trace elements via farmed and cage aggregated wild Axillary seabream (Pagellus acarne) in a copper alloy cage site in the Northern Aegean Sea.

Axillary seabream (Pagellus acarne) farmed in a copper alloy mesh pen and wild individuals of P. acarne aggregated near the copper-alloy cages presented higher concentrations of trace metals in the liver, skin and gills than in fish muscle tissues in two batches of small and large fish sizes. Elevated mean levels of metals (mg kg) in muscle tissues in both small and large fish size groups were observed in the rank order of Zn(3.