Publications by authors named "Barik A"
Background: Train collision accidents are tragic events associated with high mortality. The study aimed to comprehensively describe the clinical-epidemiological profile, disaster emergency response, and management following a train collision accident in Odisha, India.
Methods: This observational study was conducted by a tertiary care hospital in eastern India.
Pain and itch are unpleasant and distinct sensations that give rise to behaviors such as reflexive withdrawal and scratching in humans and mice. Interestingly, it has been observed that pain modulate itch through the neural circuits housed in the brain and spinal cord. However, we are yet to fully understand the identities of, and mechanisms by which specific neural circuits mediate pain-induced modulation of itch.
View Article and Find Full Text PDFArticle Synopsis
- The mechanisms behind emotional responses to chronic pain are not well understood.
- In mice with chemotherapy-induced peripheral neuropathy (CIPN), licking affected areas becomes a strong coping mechanism, especially in response to cold stimuli.
- Research identified the lateral parabrachial nucleus (LPBN) as crucial in managing this licking behavior by responding to pain signals from the spinal cord and brain, highlighting the complex interaction between pain and emotional responses.
A fast and highly sensitive electrochemical sensor (ECS) is crucially desirable for observing synthetic dyes in foodstuffs, as excessive consumption of these colorants can pose risks to human health, including toxicity and pathogenicity. This research introduces the creation of an ECS comprising a CuO-ZrO nanocomposite for detecting Sunset Yellow (SY) dye in beverage and food items. The synthesized CuO-ZrO material underwent thorough characterization using various physicochemical and electroanalytical methods.
View Article and Find Full Text PDFThe nitrogen mustard alkylating agent chlorambucil (CBL) is a critical component of chemotherapeutic regimens used in the treatment of chronic lymphocytic leukemia. The cancer cell-killing actions of CBL are limited by glutathione (GSH) conjugation, a process catalyzed by the GSH transferase hGSTA1-1 that triggers CBL efflux from cells. In the cancer cell microenvironment, intracellular GSH levels are elevated to counterbalance oxidative stress generated due to the high glycolytic demand.
View Article and Find Full Text PDFObjective: To assess the effectiveness of leukocyte-platelet-rich fibrin (L-PRF) compared with conventional treatment on canine retraction, rotation, pain, and soft tissue healing.
Methods: Sixteen adult patients aged 18-25 years (10 females, and 6 males; mean age 22.25 ± 2.
Introduction Healthcare systems around the world were disrupted by the COVID-19 pandemic. Multiple waves were experienced by most countries, and clinical symptoms and severity varied between these waves. A COVID-19 infection in pregnant women may result in complications for both the mother and the fetus and thus pose an additional challenge for clinicians.
View Article and Find Full Text PDFObjectives: To examine dentoalveolar changes following intrusion of maxillary incisors with one or two anterior miniscrews in subjects with gummy smile and deep bite.
Materials And Methods: Forty-three subjects were selected and divided into two groups: group I (22 subjects: 15 women, 7 men; mean age 30 ± 10 years) received one miniscrew between the upper central incisors, and group II (21 subjects: 16 women, 5 men; mean age 30 ± 10 years) received two miniscrews between the canines and lateral incisors. Dentoalveolar parameters, including amount of intrusion, root resorption, incisor inclination, alveolar bone thickness, and buccal alveolar crest height (cementoenamel junction to labial alveolar crest), were evaluated using cone-beam computed tomography scans obtained before and after intrusion.