Treatments for Inflammatory Arthritis: Potential But Unproven Role of Topical Copaiba.

Traditional medicines for inflammatory arthritis (IA) include nonsteroidal anti-inflammatory drugs (NSAIDs) and cyclooxygenase-2 inhibitors (COXIBs), which have variable clinical benefits and serious side effects. In large-scale randomized, controlled trials (RCTs) in IA, they have demonstrated significant decreases in pain and inflammation but also significant increases in gastrointestinal symptoms, serious bleeding, and cardiovascular events. Copaiba, an essential oil used topically, has potential but unproven benefits, with few to no side effects.

Modest dietary reductions in blood cholesterol have important public health benefits.

Large reductions in blood cholesterol produce major clinical and public health benefits. Based on extrapolations from randomized evidence, assuming no threshold, a 3% to 4% reduction in blood cholesterol would decrease risk of coronary heart disease (CHD) by 12%. If so, treating larger numbers of people at lower risk would yield greater reductions in CHD than treating smaller numbers at higher risk.

Lumbar spinal stenosis: can positional therapy alleviate pain?

Methods: We analyzed a retrospective case series of 52 patients with spinal stenosis confirmed by spinal imaging and walking limitations treated with a wheeled walker set to induce lumbosacral flexion.

Results: Of the 52 patients, improvement in ambulation was classified as excellent for 30 (58%), good for 7 (13%), moderate for 8 (16%), and poor for 7 (13%). Among 48 patients with neurogenic pain, pain relief was classified as excellent for 22 (46%), good for 11 (23%), moderate for 7 (14.