Genetic diversity of isolates from northwest of Iran during COVID-19 era.

Background: Tuberculosis (TB) is considered one of the most infectious diseases in the world. In this study, we intended to examine the epidemiology of tuberculosis by MIRU-VNTR to define the changes that occur in the transmission of tuberculosis in the region during the COVID-19 era. A total of 120 isolates were collected from sputum samples of patients referred to East Azerbaijan Center TB from December 2020 to August 2021.

Comparative antibacterial effects of ginger and marjoram extract versus conventional irrigants on mature biofilms: An study.

Background: This study evaluated antibacterial effects of Ginger and Marjoram extract compared with Routine Intracanal Irrigants on Mature Biofilms.

Material And Methods: Sixty-six extracted human teeth, were randomly assigned to four groups 5.25% sodium hypochlorite (NaOCl), 2% chlorhexidine (CHX), chloroform extract of marjoram (Origanum majorana), and oil extract of ginger (Zingiber officinale), and two positive and negative control groups (n=11).

py-MCMD: Python Software for Performing Hybrid Monte Carlo/Molecular Dynamics Simulations with GOMC and NAMD.

py-MCMD, an open-source Python software, provides a robust workflow layer that manages communication of relevant system information between the simulation engines NAMD and GOMC and generates coherent thermodynamic properties and trajectories for analysis. To validate the workflow and highlight its capabilities, hybrid Monte Carlo/molecular dynamics (MC/MD) simulations are performed for SPC/E water in the isobaric-isothermal () and grand canonical (GC) ensembles as well as with Gibbs ensemble Monte Carlo (GEMC). The hybrid MC/MD approach shows close agreement with reference MC simulations and has a computational efficiency that is 2 to 136 times greater than traditional Monte Carlo simulations.

The comparison of calcium hydroxide, curcumin, and antibacterial effects on 6-week-old biofilm as an intracanal medicament: An study.

Background: This study aimed to compare the antibacterial effects of calcium hydroxide, curcumin, and as an intracanal medicament on 6-week-old biofilm.

Materials And Methods: In this study, the solution containing ATCC 29212™ was inserted into the canals of 72 single-rooted teeth to produce biofilm. The samples were divided into four groups, and the antibacterial agent as an intracanal drug was used for 1 week.

The synergistic effect of turmeric aqueous extract and chitosan against multidrug-resistant bacteria.

We aimed to investigate the antibacterial and antibiofilm effects of turmeric and chitosan against the planktonic and biofilm forms of multidrug-resistant (MDR) bacteria. A group of MDR bacteria, including clinical isolates of methicillin-resistant Staphylococcus aureus, carbapenem-resistant Pseudomonas, carbapenem-resistant Enterobacteriaceae and AmpC-producing Enterobacteriaceae, were collected by phenotypic and genotypic assays. The broth microdilution method was used to investigate the MIC of turmeric aqueous extract and chitosan.

Evaluation of the film thickness and antibacterial property of mineral trioxide aggregate mixed with propylene glycol as a root canal sealer.

Background: The aim of this study was to compare the film thickness and antibacterial properties of mineral trioxide aggregate-propylene glycol (MTA-PG) as a sealer in comparison with MTA Fillapex and AH26 sealers.

Materials And Methods: In these study the antibacterial property of the sealers was evaluated using direct contact test in fresh and set states. was incubated in direct contact with fresh and set materials.

Evaluation of sealing abilitiy of mineral trioxide aggregate mixed with propylene glycol as a root canal sealer: A study.

Background: Sealing ability is one of the most important features of endodontic sealers. The main goal of the present study was to compare sealing ability of mineral trioxide aggregate (MTA)-propylene glycol (PG) with two commonly used resin-based and MTA-based sealers.

Materials And Methods: In This study Seventy extracted single-root teeth were used.

Detection of carbapenem-resistant Enterobacteriaceae by chromogenic screening media.

Enterobacteriaceae are a part of the human intestinal flora easily spread by hand carriage, water and food. Treatment of infections due to Enterobacteriaceae is difficult mainly in countries with a low socioeconomic state. Carbapenems are considered as a last-resort antibiotic for the treatment of infections due to multidrug-resistant Enterobacteriaceae.

Genotyping of Mycobacterium tuberculosis isolates from northwest Iran for determination on the mechanism of transmission.

Planning to control tuberculosis requires identification of dominant strains in the region, transmission patterns and risk factors that are possible by using molecular genotyping techniques. The aim of this study is to determine the transmission of tuberculosis in the northwest of Iran in order to better understand the spread of disease in northwest of Iran. In this study, 194 positive mycobacterium cultivars in northwest of Iran were investigated using exact tandem repeat-variable number tandem repeats (ETR-VNTR) method.

Antibacterial effect of different concentrations of sodium hypochlorite on biofilms in root canals.

The aim of this study was to evaluate the effectiveness of different concentrations of sodium hypochlorite (NaOCl) solution in reducing bacterial growth in Enterococcus faecalis biofilms in root canals. The root canals of maxillary central incisors of 104 subjects underwent chemomechanical debridement. In order to remove the smear layer, 5.

Frequency of and virulence genes in drug resistant clinical isolates of and their role in biofilm formation.

Objectives: has a high propensity to form biofilm and frequently causes medical device-related infections with multiple-drug-resistance in hospitals. The aim of this work is to study antimicrobial resistance and the role of and genes in biofilm formation by . to understand how this pathogen persists in the hospital environment.

Comparing the Coronal Seal of Different Thicknesses of MTA with Gutta-Percha after Post Space Preparation.

Introduction: The aim of this study was to compare the coronal seal of different thicknesses of MTA with gutta-percha after post space preparation.

Materials And Methods: A total of 50 maxillary central incisors randomly divided into 5 experimental groups (n = 8). After preparation of the root canals with step back technique, in groups 1 and 2, post spaces were prepared and 4 or 5 mm gutta-percha remained in the apical, respectively.

Apical microleakage of AH Plus and MTA Fillapex® sealers in association with immediate and delayed post space preparation: a bacterial leakage study.

Aim: The aim of the present study was to compare the apical microleakage of root canals obturated with AH Plus and MTA Fillapex® sealers.

Methods: A total of 76 anterior teeth were randomly divided into 4 groups (N.=15) and in each group 2 positive and 2 negative control teeth.

Antimicrobial efficacy of photodynamic therapy and sodium hypochlorite on monoculture biofilms of Enterococcus faecalis at different stages of development.

Background And Objective: As the Enterococcus faecalis biofilm ages, it is likely that bacteria in mature and old biofilms will become more resistant to commonly used antibacterial irrigants. Photodynamic therapy (PDT) has been used to kill resistant bacteria organized in a biofilm. This study aimed to investigate the antimicrobial effectiveness of 1% sodium hypochlorite (NaOCl), 2.

Effect of Er, Cr: YSGG laser irradiation on Enterococcus faecalis in infected root canals.

Objective: The purpose of this study was to investigate the eradication of Enterococcus faecalis by high-power settings of Er, Cr:YSGG laser irradiation in root canals of extracted teeth.

Background Data: The bacteria entering the root canal system invade dentinal tubules, resulting in persistent infections in root canals due to limited penetration of irrigation solutions into the dentinal tubules. The antibacterial effects of different lasers have been investigated in previous studies.