Evaluation of Urinary Neutrophil Gelatinase-associated Lipocalin as a Biomarker in Pediatric Vesicoureteral Reflux Assessment.

Introduction: Defining a non-invasive marker to predict the risk of kidney damage is very helpful to manage vesicoureteral reflux (VUR) in children. This study aimed to investigate the predictive value of urinary neutrophil gelatinase-associated lipocalin (uNGAL) as a non-invasive biomarker of reflux nephropathy in pediatric with primary VUR.

Methods: This case-control study was performed on 63 children with primary VUR and 72 age- and sex-matched healthy children as controls.